6/17/2025
The focus of my research is on the modulation of aldosterone production. Aldosterone is a steroid hormone produced in the outer-most layer of the adrenal gland, a zone termed the…
6/17/2025
As Paleolithic hunter gatherers, the human diet was relatively low in fats and simple carbohydrates. Technological advances, beginning with the agricultural revolution 12,000 years ago and culminating with the mechanization…
6/17/2025
Discovering and characterizing inhibitors for Sphingosine Kinase and Sphingosine 1-phosphate transporters (Spns2 and Mfsd2b)
6/17/2025
Research Interests: Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes. 1. Resolution of acute and propagation of chronic inflammation. 2. Mechanisms of endothelial-monocyte interaction in chronic…
6/17/2025
The focus of my research has been the pharmacology and physiology of adenosine receptors. Various agonists and antagonists of adenosine receptors have therapeutic uses or potential for the treatment of…
6/17/2025
Our research investigates the biology of the lipid mediator, sphingosine 1-phosphate (S1P). S1P concentration gradients are known to influence immune cell positioning. Indeed, S1P type 1 receptor agonist drugs are…
6/17/2025
6/17/2025
The major focus of my lab is to understand how the genetic drivers of cancer fuel tumor evolution and to mechanistically define how these genes contribute to various tumor phenotypes.…
6/17/2025
The primary goal of our lab is to understand the neural code underlying the generation of different motivated behaviors (e.g. feeding, drinking, and social interaction), with a focus on how…
6/17/2025
A major focus of my research program is to elucidate the role of brown adipose tissue (BAT)-derived extracellular vesicles in mediating the cardioprotective effects of the leptin/melanocortin 4 receptor (MC4R)…
