6/17/2025
In every human cell, dynamic cytoskeletal networks drive or enable critical processes such as cell division, motility, and secretion. Cytoskeletal dysregulation consequently results in cellular malfunction and several pathologies, ranging…
6/17/2025
The research focus in the Elliott Lab is to understand the function of tissue-resident macrophages as effectors of innate immunity in acute and chronic inflammation, and cancer. Macrophages are a…
6/17/2025
The systems biology research in the Fallahi-Sichani lab is focused primarily on understanding the mechanisms through which human cancer cells respond heterogeneously to environmental and therapeutic perturbations. These responses can…
6/17/2025
Our research program is concerned with the synthesis, properties and applications of metal complexes with polymeric ligands. These multifunctional targets are prepared by combining coordination chemistry with living polymerization methodologies.…
6/17/2025
Our lab is interested in the molecular and cellular basis of human disease, with a focus on aberrant signal transduction of protein kinases in ciliopathies, a class of human diseases…
6/17/2025
We aim to understand how eukaryotic cells control chromatin structure. Knowledge of chromatin-structure at the level of its nucleosome subunits inside cells will give far-reaching mechanistic insight into gene regulation,…
6/17/2025
Renin-synthesizing cells are crucial in the regulation of blood pressure and fluid and electrolyte homeostasis. These cells have been considered as terminally differentiated because they synthesize a hormone, are few…
6/17/2025
Our goal is to understand the molecular mechanisms by which cells move, with particular emphasis on muscle contraction. We examine the mechanics of these processes at the level of individual…
6/17/2025
Research in the Güler Malaria Lab focuses on the human-infective malaria parasite, Plasmodium falciparum. Some of our projects are described below: ·We are interested in underlying mechanisms that drive genetic change…
6/17/2025
Why do some animals have the ability to regenerate certain tissues and organs, while others have lost this capacity? The study of regenerative biology and medicine have shown that the…
