6/17/2025
In eukaryotes, approximately 30% of all newly synthesized proteins pass through the endoplasmic reticulum (ER), where they undergo folding and maturation. A significant fraction of nascent proteins may fail to…
6/17/2025
The research in my lab focuses primarily on the cellular mechanisms of implantation and gastrulation in the mouse embryo. In particular , we have been investigating the regulation of motility…
6/17/2025
Agnieszka Swiatecka-Urban studied the regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells. One focus of her research activity has been the characterization of mechanisms and…
6/17/2025
Our lab studies the structure and function of several membrane proteins of clinical importance in their natural membrane environment. We are also interested in the roles that membrane lipids play…
6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…
6/17/2025
6/17/2025
Papillomaviruses cause the most common lethal malignancy in women world-wide: cervical cancer. Our laboratory studies the actions of the papillomavirus E6 oncoprotein. By identifying host proteins that associate with E6,…
8/22/2025
Cellular activities are compartmentalized by lipid membranes with complex, dynamic lipid compositions, which determine many collective properties (fluidity, permeability, stiffness, lateral heterogeneity, trans-bilayer asymmetry, etc.) that enable cellular functions. These…
6/17/2025
The primary focus of our work is to develop a fundamental understanding of the mechanisms that govern the formation of multinucleated cell types produced by cell-cell fusion – making one…
