6/17/2025
Alu RNA transcripts promote advanced dry age-related macular degeneration:Geographic atrophy (GA) is the advanced form of dry age-related macular degeneration and is a leading cause of blindness in the Unites…
6/17/2025
Research Projects Engineering T cells to overcome suppressive signals in the tumor microenvironment Engineered T cell therapy can effectively kill ovarian cancer cells, but there are still tumor-driven hurdles that T cells…
6/17/2025
The Arandjelovic laboratory research focus is on cell clearance in inflammatory disease, using rheumatoid arthritis (RA) and multiple sclerosis (MS) as model systems. Inflammatory states are associated with high rates…
6/17/2025
My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells' changing microenvironment direct their phenotype…
6/17/2025
The Bauer laboratory is focused on developing novel therapies for the treatment of pancreatic cancer and colorectal cancer.
6/17/2025
Research in our laboratory is now focused primarily on Alzheimer’s disease (AD), the most common form of a group of neurodegenerative disorders known collectively as tauopathies. The histopathological hallmark of…
6/17/2025
The focus of our work is on the use of costimulatory pathways, particularly the CD70-CD27 TNF-superfamily members, to promote immunotherapeutic T cell responses against melanoma and other malignancies, and as…
6/17/2025
Arf family GTPases and their function in membrane trafficking and cell motility Cell biology of bacterial infection The innate immune response to bacterial infection
6/17/2025
6/17/2025
The goal of our laboratory is to understand the genetic mechanisms that lead to increased susceptibility to cardiovascular and metabolic diseases. The interactions among hundreds of genes and gene networks…