6/17/2025
6/17/2025
1. Detection of genomic variation: I have developed several methods to identify and map variants (SNPs, indels, and large-scale rearrangements) from large-scale sequencing datasets. This includes identification and genotyping of…
6/17/2025
Our research on viruses provides insight not only into the diseases they cause, but it also leads to the discovery of novel basic mechanisms that operate in eukaryotic cells. Over…
6/17/2025
Dr. Rich's research is centered on understanding the genetic epidemiology of complex human disease, including the genes contributing to atherosclerosis, stroke and intermediate phenotypes (risk factors). These studies range from…
6/17/2025
The post-genomic era is marked by the development of technologies which have revealed the astonishing molecular diversity of gene products. Multiple distinct protein forms, or “proteoforms”, can arise through several…
6/17/2025
My primary research interest is in atherosclerosis, which is the cause of heart attack, stroke and peripheral arterial disease. Although mortality from atherosclerosis has had a decline in past few…
6/17/2025
Basic, autonomous and higher, voluntary cognitive functions of the brain require production of an immense diversity of neuron types at the right place and time, as well as correct wiring…
6/17/2025
Transcriptional silencing Understanding how chromatin structure influences DNA-mediated processes has become a fundamental problem in cellular biology. Chromatin is known to influence the regulation of eukaryotic gene expression, DNA replication, DNA…
9/3/2025