6/17/2025
Defects in chromosome segregation can generate aneuploidy, a condition that is found in almost all human tumors and is the major cause of miscarriages and birth defects. The complex process…
6/17/2025
The research in my lab focuses primarily on the cellular mechanisms of implantation and gastrulation in the mouse embryo. In particular , we have been investigating the regulation of motility…
6/17/2025
Agnieszka Swiatecka-Urban studied the regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells. One focus of her research activity has been the characterization of mechanisms and…
6/17/2025
Research in my laboratory currently focuses on several very different aspects of plant cell growth and differentiation. One area of current interest is an examination of the biochemical, cellular, and…
6/17/2025
My research and career goal is to develop expertise in the development of medications for the addictions. In addition, I plan to link clinical psychopharmacological research with basic biochemical studies…
6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…
6/17/2025
Our research focus is to understand the structure and function of unusual DNA sequences in living cells, and how these sequences cause genome instability and lead to human diseases. Human…
6/17/2025
Our mission is to understand how signaling molecules mediate cardiomyocyte growth, hypertrophy, and heart failure. We use novel approaches based on fruit fly genetics to identify genes that cause or…
6/17/2025
How do tissues regenerate after damage? What are the mechanisms that allow cells to coordinate regeneration? The Worley lab combines experimental genetics, developmental biology, and single-cell transcriptomics to uncover the…
6/17/2025
Analysis of the role of TGIFs during development. TGIF proteins are transcriptional repressors, which regulate TGFβ signaling and have been suggested to repress retinoid regulated gene expression. Mutations in human TGIF…
