6/17/2025
Our lab develops methods based on microfluidic culture systems, bioanalytical techniques, and spatially resolved simulations to quantify the spatiotemporal dynamics of the inflammatory cascade and develop targeted therapies. This work…
6/17/2025
My laboratory aims to explore the physiological role of endoplasmic reticulum (ER) homeostasis (with a special focus on ER-associated degradation, ERAD) in the context of human diseases. We use genetic,…
6/17/2025
Our research on viruses provides insight not only into the diseases they cause, but it also leads to the discovery of novel basic mechanisms that operate in eukaryotic cells. Over…
6/17/2025
Dr. Rich's research is centered on understanding the genetic epidemiology of complex human disease, including the genes contributing to atherosclerosis, stroke and intermediate phenotypes (risk factors). These studies range from…
6/17/2025
Humans are colonized with trillions of microorganisms, collectively termed the microbiota. Aside from providing a first line of defense to invading pathogens or aiding in digestion and metabolism, commensal microbes…
6/27/2025
Atherosclerosis is a chronic inflammatory disease whose late-stage clinical complications including myocardial infarction (heart attack) and stroke, are the leading causes of death worldwide. Clinical trials of anti-inflammatory therapies yield…
6/17/2025
The Spencer lab studies host-pathogen interactions of Gram-positive bacteria, focusing on the major neonatal pathobiont Group B Streptococcus (GBS). GBS can asymptomatically colonize the female genital tract, leading to transmission…
6/17/2025
The Sperling lab focuses on the role of the immune system in the development and progression of lung disease. In mouse models, we have made significant contributions to our understanding…
6/17/2025
The Sun Lab at the University of Virginia investigates how the immune system responds to viral infections, chronic conditions, and aging, with particular emphasis on long COVID, cancer and aging…
6/17/2025
My interests are in the areas of iron metabolism, macrophages, fibrosis, vascular calcification and progressive kidney diseases.
