6/17/2025
Structural biology of membrane proteins: Membrane proteins represent about ~25% of all proteins in any given genome carrying out many vital functions (transporters, receptors, channels, etc..). Membrane proteins also represent ~50%…
6/17/2025
Our research focuses on the application of chemical engineering principles to problems in microbial ecology. The aim is to develop a fundamental understanding of mechanisms underlying microbial behavior which will…
6/17/2025
We develop nanoscale imaging methods for 3D single-molecule localization in intact bacterial cells. Our two primary research objectives are: 1. Development of 3D super-resolution imaging methods, including instrument design, sample preparation,…
6/17/2025
Ongoing work in my laboratory focuses on the role of an alternative splicing factor, the RNA helicase DDX39B, known to immunologists as BAT1, on immunity and autoimmunity. The connection to…
6/17/2025
Multiple Sclerosis is a currently incurable autoimmune disease that affects 400,000 Americans and millions worldwide. The disease is characterized by destruction of myelin, the protective coat that wraps neuronal axons…
6/17/2025
Research in the Güler Malaria Lab focuses on the human-infective malaria parasite, Plasmodium falciparum. Some of our projects are described below: ·We are interested in underlying mechanisms that drive genetic change…
6/17/2025
My research is focused on elucidating the immunoregulatory mechanism by Hepatitis C virus (HCV). HCV is a global health concern causing severe liver disease such as fibrosis, cirrhosis and hepatocellular…
6/17/2025
Toxoplasma gondii is an intracellular, protozoan parasite that infects approximately one-third of the world population. The parasite can be acquired congenitally or in adults, through the ingestion of contaminated food…
6/17/2025
The goal of the primary research project in the Hughes laboratory is to investigate a select family of host interferon-inducible CXC chemokines known as CXCL9, CXCL10, and CXCL11 as novel…
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
