6/17/2025
Neural regeneration within the central nervous system (CNS) is a critical unmet challenge as CNS disorders continue to be the leading cause of disability nationwide. Engineers can provide a unique…
6/17/2025
Tracy Larson explores the origins, functions, and mechanisms underlying natural variation in the spatial and temporal patterns of adult neurogenesis by integrating behavioral genomics, comparative neuroanatomy, and cellular biology with…
6/17/2025
My lab is interested in epithelial homeostasis, secretion and innate defense. We focus on the human prosecretory mitogen 'lacritin' that we discovered and named out of an unbiased screen for…
6/21/2025
Our laboratory is interested in the cellular mechanisms of neuronal vulnerability associated with stroke. A multidisciplinary approach has been undertaken to elucidate how neurons are destabilized during ischemia and what…
6/17/2025
Our goal is to understand the biological basis of cognition. After many experimental studies elucidating the rules of associative synaptic modification, almost all of our research uses the tools of…
6/17/2025
Targeted therapy: by serendipity, we identified a novel oncogene, and found that multiple cancers are addicted to its activity. This oncogene addiction is evidenced in glioblastoma, pediatric sarcoma, and others.…
6/17/2025
I am interested in understanding the molecular mechanisms that control the generation of different neuronal types along the anterior-posterior (A-P) axis of the spinal cord, using motor neurons as a…
6/17/2025
I have been interested in understanding the regulation and misregulation of retinal structures and functions during normal development and in diseased conditions since my PhD study. I started my own…
6/17/2025
Oligodendrocyte precursor cells (OPCs, or NG2 glia) comprise the largest pool of progenitor cells in the brain and continuously generate myelin-producing oligodendrocytes throughout our life until aging onset. However, how…
6/17/2025
1. Wnt and PCP signaling in mechanosensory hair cell polarity. The actin-based hair bundle atop sensory hair cells is the mechanotransduction organelle essential for hearing and balance. A majority of sensorineural…
