6/17/2025
Our goal is to understand how the brain integrates sensory feedback to control specific autonomic responses that restore physiologic balance. We are also interested in the cross-talk between cardiorespiratory physiology…
6/17/2025
The Ai lab specializes in protein engineering and employs interdisciplinary approaches, including biophysics, bioanalytical chemistry, chemical biology, synthetic biology, and optical imaging. One of our main areas of focus is the…
6/17/2025
Alu RNA transcripts promote advanced dry age-related macular degeneration:Geographic atrophy (GA) is the advanced form of dry age-related macular degeneration and is a leading cause of blindness in the Unites…
6/17/2025
Neurooncology (cancer genetics), neurocutaneous disorders (neurofibromatosis type 1 and 2, von Hippel-Lindau disease, tuberous sclerosis, Sturge-Weber syndrome), acoustic neuroma/vestibular schwannoma, hearing loss, meningioma, ependymoma, hemangioblastoma.
6/17/2025
Mutations in any one of hundreds of genes cause neurodevelopmental disorders, like autism spectrum disorders and intellectual disability. For some unique genes, either an increase or decrease in their expression…
6/17/2025
Signaling between cells in the brain relies on electrical and chemical transmission. Ion channels traverse brain cell membranes to serve as conduits for the flow of ionic current, which creates…
6/17/2025
Our lab aims to understand how the brain generates complex electrical signals, and how these signals are used to process information. A major extension of this aim is to understand…
6/17/2025
Research in our laboratory is now focused primarily on Alzheimer’s disease (AD), the most common form of a group of neurodegenerative disorders known collectively as tauopathies. The histopathological hallmark of…
6/17/2025
Our lab is involved in studying the development of the brain. We always have a number of projects underway, with a focus on understanding the development of the ventral forebrain.…
6/17/2025
Membranes and membrane proteins participate in some of the most important and interesting cellular processes. Energy transduction, cell signaling, membrane excitability, secretion and immune recognition are examples of a few…