6/17/2025
All eukaryotic cells divide by assembling a microtubule-based spindle machinery that equally segregates chromosomes between daughter cells. The faithful segregation of chromosomes during cell division is essential as errors in…
6/17/2025
Our research on viruses provides insight not only into the diseases they cause, but it also leads to the discovery of novel basic mechanisms that operate in eukaryotic cells. Over…
6/17/2025
The post-genomic era is marked by the development of technologies which have revealed the astonishing molecular diversity of gene products. Multiple distinct protein forms, or “proteoforms”, can arise through several…
6/17/2025
My laboratory studies the biological conflict between bacteria and the viruses that infect them: bacteriophages (phages). Bacteriophages are the most abundant entity on the planet, and are crucial for controlling…
6/17/2025
Our lab studies the structure and function of several membrane proteins of clinical importance in their natural membrane environment. We are also interested in the roles that membrane lipids play…
6/17/2025
Our research focuses on the molecular mechanisms of mitochondrial calcium transport and signaling. We aim to understand how these mitochondrial processes contribute to cardiovascular and neuronal physiology, as well as…
6/17/2025
The genomic DNA of eukaryotes is packaged into chromatin through a fundamental repeating unit known as the nucleosome. In this chromatin environment, our genomic DNA is constantly exposed to a…
6/17/2025
6/17/2025
Under certain conditions, all essential biopolymers, such as polypeptides, nucleic acids and polysaccharides, have to cross at least one membrane to reach their final destinations. Examples include the secretion of…
