6/17/2025
Our research investigates the biology of the lipid mediator, sphingosine 1-phosphate (S1P). S1P concentration gradients are known to influence immune cell positioning. Indeed, S1P type 1 receptor agonist drugs are…
6/17/2025
Our research is in the field of human genetics. Specifically, we are studying the molecular genetics and biology of myotonic dystrophy (DM), the most common inherited neuromuscular disorder in adults.…
6/17/2025
I'm interested in translational science, economic, and computational methods that support evidence integration in precision medicine to allow patients, families, clinicians, and health systems to make decisions about novel therapeutics.…
6/17/2025
6/17/2025
The major focus of my lab is to understand how the genetic drivers of cancer fuel tumor evolution and to mechanistically define how these genes contribute to various tumor phenotypes.…
6/17/2025
Within cells there exists a fine balance between survival and death. One of the earliest steps in the development of cancer is the ability of a cell to escape death.…
6/17/2025
Specific Research Ongoing in the McNamara lab Discovery of a single nucleotide polymorphism (SNP) in the human ID3 gene that is functionally relevant and associated with vascular disease in humans. The…
6/17/2025
6/17/2025
The overarching goal of our research is functional understanding of molecular alterations in lung cancer. To that end, we determine impacts of genomic and transcriptomic alterations on tumor development and…
6/17/2025
The Patel lab focuses on understanding the cellular mechanisms by which seizures are initiated in SCN8A epileptic encephalopathy (DEE13). SCN8A EE is a severe genetic epilepsy syndrome caused by de…
