6/17/2025
As Paleolithic hunter gatherers, the human diet was relatively low in fats and simple carbohydrates. Technological advances, beginning with the agricultural revolution 12,000 years ago and culminating with the mechanization…
6/17/2025
The broad interest of the Jiang lab is how gene regulation at the chromatin, transcriptional, and post-transcriptional levels controls the stability and plasticity of cell identity, how dysregulation of these…
6/17/2025
Epigenetic changes accompany an individual’s development, aging, and disease. They’re particularly significant markers for cancer’s onset and progression, posing substantial therapeutic challenges. Increasing evidence suggests that DNA replication stress leads…
6/17/2025
Dr. Loughran's current research includes: current research includes: • R01 grant from the NIH’s National Cancer Institute to identify and characterize the LGL leukemia virus and understand how it might cause leukemia; •…
6/17/2025
My laboratory uses behavioral, pharmacological, and molecular techniques to delineate the neurobiological basis of addiction. We are particularly interested in determining the biological basis of sex differences in vulnerability to…
6/17/2025
Within cells there exists a fine balance between survival and death. One of the earliest steps in the development of cancer is the ability of a cell to escape death.…
6/17/2025
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing…
6/17/2025
My laboratory focuses on understanding the molecular and epigenetic mechanisms involved in the regulation of normal hematopoiesis and hematologic malignancies. The ultimate goal of our research is to identify new…
6/17/2025
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or StrokeAtherothrombosis, resulting from rupture or…
6/17/2025
The overarching goal of our research is functional understanding of molecular alterations in lung cancer. To that end, we determine impacts of genomic and transcriptomic alterations on tumor development and…