6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…
6/17/2025
Papillomaviruses cause the most common lethal malignancy in women world-wide: cervical cancer. Our laboratory studies the actions of the papillomavirus E6 oncoprotein. By identifying host proteins that associate with E6,…
6/17/2025
Research Projects Targeting the intersection of cancer cell-intrinsic signaling and innate immunity The innate immune cells are often suppressed within the tumor microenvironment or co-opted to promote tumor progression and metastasis. Our…
6/17/2025
Despite advancements in melanoma treatment with immune checkpoint blockade (ICB) and BRAF-targeted therapy, 40-65% of metastatic melanoma patients do not survive beyond five years. An observed 'obesity paradox' shows improved…
