6/17/2025
The post-genomic era is marked by the development of technologies which have revealed the astonishing molecular diversity of gene products. Multiple distinct protein forms, or “proteoforms”, can arise through several…
6/17/2025
My primary research interest is in atherosclerosis, which is the cause of heart attack, stroke and peripheral arterial disease. Although mortality from atherosclerosis has had a decline in past few…
6/17/2025
Basic, autonomous and higher, voluntary cognitive functions of the brain require production of an immense diversity of neuron types at the right place and time, as well as correct wiring…
6/17/2025
Transcriptional silencing Understanding how chromatin structure influences DNA-mediated processes has become a fundamental problem in cellular biology. Chromatin is known to influence the regulation of eukaryotic gene expression, DNA replication, DNA…
6/17/2025
Defects in chromosome segregation can generate aneuploidy, a condition that is found in almost all human tumors and is the major cause of miscarriages and birth defects. The complex process…
6/17/2025
The research in my lab focuses primarily on the cellular mechanisms of implantation and gastrulation in the mouse embryo. In particular , we have been investigating the regulation of motility…
6/17/2025
Research in my laboratory currently focuses on several very different aspects of plant cell growth and differentiation. One area of current interest is an examination of the biochemical, cellular, and…
6/17/2025
My research and career goal is to develop expertise in the development of medications for the addictions. In addition, I plan to link clinical psychopharmacological research with basic biochemical studies…
6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…