Pediatric Center of Excellence

The Center of Excellence in Pediatric Nephrology strives to provide a coordinated, interdisciplinary, and inter-institutional approach to studying the development of the kidney during embryonic, fetal and postnatal life. The center brings together investigators from the University of Virginia and Tulane University. The main research theme is “Kidney Development and Disease: Cell Fate and Precursors of Disease in the Young and Adult.” Broadly, the proposed research deals with fundamental questions of clinical relevance in Pediatric Nephrology such as the understanding of kidney morphogenesis and homeostasis in health and disease. The experimental approaches range from examination of epigenetic mechanisms that control cell fate, plasticity, and identity and the cellular signals underlying the phenotypic transformation that occurs during kidney injury and repair.

Summer Students in Lab Opportunity

The UVA NIH Pediatric Center of Excellence in Nephrology will support four 2024 Summer students in our labs. This is a full-time position (40 hours per week) during the summer break (minimum 8 weeks and a stipend of approx. $15/hour; for students currently enrolled in or recently graduated from an accredited college or university). Students will be learning and working on current projects of the lab under the direct supervision of other lab members.

Interested candidates should send an email to Jalen Hill ( and Dr. Sequeira-Lopez ( with their CV, GPA, and transcripts and request a letter of support from a mentor/teacher.

Deadline: April 1st, 2024.

Accepted candidates will be notified by mid- end of April.


UVA Discovery a Major Step Toward Growing Kidneys

Researchers at the Pediatric Center of Excellence in Nephrology at UVA have identified the cells that give rise to the blood vessels within the kidney.

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Call for Pilot & Feasibility Proposals in Pediatric Kidney Disease Cycle 2: 2024 Start Date

The Pediatric Centers of Excellence in Nephrology (PCENs) at the University of Virginia (UVA), Children’s Hospital of Philadelphia (CHOP), and Washington University in St. Louis (WashU) are issuing a joint RFA for Pilot and Feasibility (P&F) projects. The PCEN program is funded by the National Institute of Diabetes and Digestive and Kidney Diseases.

Photo of The Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA)

Central Research

Researchers at the center are focused on two main projects: RBPJ and cell fate in the kidney vasculature and regenerative capacity of the kidney after ureteral obstruction release.

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Photo of family at The Pediatric Center of Excellence in Nephrology (PCEN) at the University of Virginia (UVA)

Pilot Program

The pilot and feasibility program encourages young and established investigators to take up research relevant to kidney development and disease and speed the acquisition of knowledge that can be applied to treatment of children with renal and urological diseases.

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Photo of medical professional at the UVA Pediatric Center of Excellence in Nephrology

Enrichment Program

The center aims to inspire, attract and stimulate the interest of young individuals in Pediatric Nephrology research.

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National Institute of Diabetes and Digestive and Kidney Diseases

NIDDK conducts and supports research on many of the most common, costly, and chronic conditions to improve health.