Professor, Medicine: Endocrinology and Metabolism
- MD, MBBS, Internal Medicne, Jawaharlal Institute of Postgraduate Medical Education and Research [JIPMER]
- MRCP, Internal Medicine, Royal College of Physicians (London, UK)
- board certification, Internal Medicine, Mayo Clinic, Rochester, MN
- board certification, Endocrinology, Mayo Clinic, Rochester, MN
- Fellowship, Medicine, Royal College of Physicians (London, UK)
560 Ray C Hunt Drive, Ivy Building
Room 3106, Center of Diabetes Technology, Division of Endocrinology, University of Virginia School of Medicine
Charlottesville, VA 22908
Integrative approaches to Close the Loop in Type 1 diabetes
*Artificial pancreas for type 1 diabetes. Dr. Basu's research is currently directed at developing physiological models to inform, fine tune and eventually personalize an effective closed-loop control artificial pancreas system for patients with type 1 diabetes using cutting-edge insulin pump and glucose sensor technologies.
These models are designed to assess the effect of sizes of meals, ranges of physical movement that span all activities of daily living, exercise, sleep, menstruation and pregnancy (among others) as they modulate insulin action and glucose variability. Such information is critical to refine and personalize control algorithms that will then be applied to individualize artificial pancreas systems.
Furthermore, the innovative approach to investigate pancreatic alpha cell function, in vivo, in humans using a novel isotope dilution technique with stable isotopes of glucagon, will provide critical needed information on dysregulation of alpha cell function in type 1 diabetes that would further refine mutli-hormone closed loop control in type 1 diabetes in the future.