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Division of Endocrinology & Metabolism

Sue Brown, MD

Sue Brown MDPRIMARY APPOINTMENT:

Professor of Medicine, Endocrinology, and Metabolism

CONTACT:

PO Box 801420
Telephone:434.924.1825
Fax: 434.924.9616
Email:sab2f@virginia.edu

TRAINING:

  • MD, University of Virginia
  • Residency, Internal Medicine, the University of North Carolina at Chapel Hill
  • Fellowship, Endocrinology, the University of North Carolina at Chapel Hill

RESEARCH INTERESTS:

Treatment options for type 1 diabetes with a focus on automated insulin delivery systems.

RESEARCH SUMMARY:

Dr. Brown’s clinical research is focused on new treatment options for type 1 diabetes. Dr. Brown is Medical Director of the Center for Diabetes Technology and works in collaboration with engineers and mathematicians. She has been a principal investigator on multiple NIH-funded, and FDA-regulated clinical trials focused on type 1 diabetes. These clinical research programs aim to further identify glycemic variability factors in people with type 1 diabetes, particularly glucose changes surrounding exercise, meals, and the menstrual cycle. The Center for Diabetes Technology is actively developing automated insulin delivery systems for people with type 1 diabetes. Dr. Brown was the study chair for at least two major randomized-controlled multi-site US trials on automated insulin delivery that ultimately led to FDA approval of a system in current use in the US (Brown et al, NEJM 2019) and another under consideration by the FDA (Brown et al, Diabetes Care 2021).

Dr. Brown is a Principal Investigator for four NIH research grants: (1) R01 DK085623 (NIDDK; “Bio-behavioral Human Machine Co-Adaptation of the Artificial Pancreas”, (2) R01 DK129553 (NIDDK; “Advanced Artificial Pancreas Systems to Enable Fully Automated Glycemic Control in Type 1 Diabetes Mellitus”), (3) R01 DK133148 (NIDDK; “Adaptive Motif-Based Control (AMBC): A Fundamentally New Approach to Automated Treatment Optimization for Type 1 Diabetes), and (4) R01 DK138366 (NIDDK: “Automated Insulin Delivery for INpatients with DysGlycemia (AIDING): Randomized Control Trial”). This work aims to develop fully automated insulin delivery systems that do not require carbohydrate counting and further understand and optimize the use of automated insulin delivery in improving the lives of people with Type 1 Diabetes.

Dr. Brown has previously been a principal investigator on an NIH K23 mentored clinical research award focusing on the effects of lactation on bone physiology.

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DEPARTMENT OF MEDICINE