6/17/2025
My group is involved in several projects focused on molecular diagnostic tools for infectious diseases. Most work involves developing panels of PCR-based diagnostic tests to detect a broad range of…
6/17/2025
The goal of the primary research project in the Hughes laboratory is to investigate a select family of host interferon-inducible CXC chemokines known as CXCL9, CXCL10, and CXCL11 as novel…
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
6/17/2025
Pathogenesis of Kaposi's Sarcoma-Associated Herpesvirus Kaposi's sarcoma (KS) remains one of the two most common AIDS-associated malignancies and is caused by the human herpesvirus, KSHV, first discovered in 1994. Nevertheless,…
6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
6/17/2025
Evaluation of molecular epidemiology tools and in vitro detection of resistance through translational research at UVA based on a multi-species outbreak of Klebsiella pneumoniae carbapenemase (KPC) producing organisms. Through the…
6/17/2025
Within cells there exists a fine balance between survival and death. One of the earliest steps in the development of cancer is the ability of a cell to escape death.…
6/17/2025
Dr. Nataro's multi-disciplinary research program focuses on enteric bacterial infections, principally diarrheagenic E. coli and Shigella spp. His seminal observations include the discovery of enteroaggregative and diffusely adherent E. coli…
6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…
