6/17/2025
Glial cells support normal brain function by maintaining ion and neurotransmitter homeostasis, by regulating local blood flow and by stabilizing the blood brain barrier. Many diseases present with an impairment…
6/17/2025
Our laboratory conducts research at the interface of chemistry and biology by employing new chemical tools and design principles to better understand fundamental aspects of cellular communication. Our research program…
6/17/2025
Defects in chromosome segregation can generate aneuploidy, a condition that is found in almost all human tumors and is the major cause of miscarriages and birth defects. The complex process…
6/17/2025
The Sun Lab at the University of Virginia investigates how the immune system responds to viral infections, chronic conditions, and aging, with particular emphasis on long COVID, cancer and aging…
6/17/2025
In eukaryotes, approximately 30% of all newly synthesized proteins pass through the endoplasmic reticulum (ER), where they undergo folding and maturation. A significant fraction of nascent proteins may fail to…
6/17/2025
The Taylor lab is focused on unlocking the potential of B cells to protect against infection, cancer, and other diseases where these cells could benefit human health. B cells are…
6/17/2025
Papillomaviruses cause the most common lethal malignancy in women world-wide: cervical cancer. Our laboratory studies the actions of the papillomavirus E6 oncoprotein. By identifying host proteins that associate with E6,…
6/17/2025
Analytical Neurochemistry I am interested in the development and characterization of analytical techniques to measure neurochemical changes. Measurements in the brain are challenging because zeptomole quantities of neuroactive molecules must be…
6/17/2025
Hematopoietic stem cells produce multiple blood cell types and replenish themselves through a self-renewal process. As with all cells, hematopoietic stem cells accumulate somatic mutations with age. While most mutations…
6/17/2025
Research Projects Targeting the intersection of cancer cell-intrinsic signaling and innate immunity The innate immune cells are often suppressed within the tumor microenvironment or co-opted to promote tumor progression and metastasis. Our…
