6/17/2025
6/17/2025
My lab is interested in epithelial homeostasis, secretion and innate defense. We focus on the human prosecretory mitogen 'lacritin' that we discovered and named out of an unbiased screen for…
6/17/2025
Dr. Le’s research focuses on neural-crest derived tissue development, regeneration and tumorigenesis, in particular the biology of neurofibromatosis. His laboratory investigates how genetic and tumor microenvironmental factors interplay to regulate…
6/17/2025
The overall goal of our research is to understand the fundamental mechanisms by which membranes and dietary lipids regulate cell physiology. By understanding the cell biology of lipids and membranes,…
6/17/2025
1. Wnt and PCP signaling in mechanosensory hair cell polarity. The actin-based hair bundle atop sensory hair cells is the mechanotransduction organelle essential for hearing and balance. A majority of sensorineural…
6/17/2025
6/17/2025
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing…
6/17/2025
Innate immunity provides the first line of defense against pathogens, which is critically important to limit their replication and spread. However, overactivation of innate immunity causes autoimmune diseases and may…
6/17/2025
All the way up to the 20th century, the human genome has been optimized to survive in environments characterized by fluctuations between periods of feast and famine. These survivor-genomes clash…
6/17/2025
The Pani lab pursues curiosity-driven research exploring the cell biological foundations of development and tissue maintenance. Cell-cell signaling performs critical functions in development, homeostasis, and disease. In normal conditions, cell signaling…
