6/17/2025
6/17/2025
Specific Research Ongoing in the McNamara lab Discovery of a single nucleotide polymorphism (SNP) in the human ID3 gene that is functionally relevant and associated with vascular disease in humans. The…
6/17/2025
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing…
6/17/2025
My laboratory focuses on understanding the molecular and epigenetic mechanisms involved in the regulation of normal hematopoiesis and hematologic malignancies. The ultimate goal of our research is to identify new…
6/17/2025
Genomic analysis of primary human cancer specimens for global genetic and gene expression alterations. Development of model systems to validate biological roles of candidate genes. Translation of experimental findings to…
6/17/2025
Tyrosine phosphorylation is a protein modification that can occur during or after translation of a protein.The phosphate addition to a tyrosine residue, regulated by tyrosine kinases and phosphatases, can result…
6/17/2025
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or StrokeAtherothrombosis, resulting from rupture or…
6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…
6/17/2025
My laboratory studies how nuclear transport and signal transduction control the compartmentalization and activity of transcription factors, particularly in the context of prostate cancer. A major focus of these studies…
6/17/2025
The Important Role of the Microcirculation: Every organ in the body is dependent on blood flow to provide the necessary oxygen and nutrients in order to stay alive. The circulatory system…
