6/17/2025
Ongoing work in my laboratory focuses on the role of an alternative splicing factor, the RNA helicase DDX39B, known to immunologists as BAT1, on immunity and autoimmunity. The connection to…
6/17/2025
Multiple Sclerosis is a currently incurable autoimmune disease that affects 400,000 Americans and millions worldwide. The disease is characterized by destruction of myelin, the protective coat that wraps neuronal axons…
6/17/2025
The goal of my research is to understand the mechanistic underpinnings of the cell signaling network that contribute to cancer progression and resistance to therapy. My laboratory is currently focused…
6/17/2025
The lab has two related areas of interest: 1) development of red cells and platelets within bone marrow precursors, and 2) the effects of iron deprivation on red cell and…
6/17/2025
Our goal is to understand the molecular mechanisms by which cells move, with particular emphasis on muscle contraction. We examine the mechanics of these processes at the level of individual…
6/17/2025
Research in the Güler Malaria Lab focuses on the human-infective malaria parasite, Plasmodium falciparum. Some of our projects are described below: ·We are interested in underlying mechanisms that drive genetic change…
6/17/2025
As Paleolithic hunter gatherers, the human diet was relatively low in fats and simple carbohydrates. Technological advances, beginning with the agricultural revolution 12,000 years ago and culminating with the mechanization…
6/17/2025
My research is focused on developing medical diagnostic imaging agents and drug discovery/delivery for therapeutic applications. Projects are from chemistry, cell study, animal study, and translational development for clinical trials.…
6/17/2025
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
