6/17/2025
Mutations in any one of hundreds of genes cause neurodevelopmental disorders, like autism spectrum disorders and intellectual disability. For some unique genes, either an increase or decrease in their expression…
6/17/2025
My laboratory develops and applies computational statistics methods to functional genomic data with a focus on epigenetic data. Epigenetics is the study of heritable phenotypic traits not coded in the…
6/17/2025
DNA replication-coupled repair, genome integrity networks, DNA damage tolerance pathways.
6/17/2025
6/17/2025
Project Title: Pathogenesis of Infections by Herpes Simplex Virus Herpes simplex virus is widespread in the human population with most people exposed during childhood. Nearly all adults have specific antibodies. HSV-1…
6/17/2025
A main goal of research in the Brown Lab centers on the genetics of host resistance to viral infection, and the role of natural killer (NK) cells in viral immunity.…
6/17/2025
My research focuses on unravelling the complex genetic mechanisms underlying risk of colorectal cancer in order to enhance disease surveillance leading to improved health outcome. Our approach integrates large-scale human…
6/17/2025
My research focuses on the design and statistical analysis of human gene mapping data. Recently, my research has focused on the development of methods for analyzing genome-wide SNP data in…
6/17/2025
The goal of our laboratory is to understand the genetic mechanisms that lead to increased susceptibility to cardiovascular and metabolic diseases. The interactions among hundreds of genes and gene networks…
6/17/2025
Overview. I work at the interface of virology and genetics to reveal core principles of viral and host gene expression. I seek to understand how viruses manipulate the transcriptional machinery…