6/17/2025
The etiology of many cardiovascular diseases can be traced to the microcirculation, which is the primary focus of the Isakson lab. For example, high blood pressure as well as strokes…
6/17/2025
6/17/2025
1) Seizures as brain explorers: A few thousand neurons acting together can generate a seizure, but it travels far from its origin, generating convulsive and dystonic movements, triggering and erasing…
6/17/2025
Discovering and characterizing inhibitors for Sphingosine Kinase and Sphingosine 1-phosphate transporters (Spns2 and Mfsd2b)
6/17/2025
Cardiovascular magnetic resonance imaging is a powerful technology that has evolved into a comprehensive imaging approach to cardiovascular disease. A major focus of our work is on developing clinical applications…
6/17/2025
The long-term goal of our research program is to elucidate the roles of peripheral and central glia and glial-glial interactions during nervous system development, maintenance and disease/injury. Using Danio rerio…
6/17/2025
WE USE FROGS TO STUDY DEVELOPMENT, DISEASE, AND REGENERATION PRECISION MEDICINE OF BIRTH DEFECTS Every parent that loses their baby to a birth defect wants to know why and if it will…
6/17/2025
My lab is interested in epithelial homeostasis, secretion and innate defense. We focus on the human prosecretory mitogen 'lacritin' that we discovered and named out of an unbiased screen for…
6/17/2025
Research Interests: Role of lipid oxidation products in inflammation and vascular immunology in atherosclerosis and diabetes. 1. Resolution of acute and propagation of chronic inflammation. 2. Mechanisms of endothelial-monocyte interaction in chronic…
6/17/2025
Targeted therapy: by serendipity, we identified a novel oncogene, and found that multiple cancers are addicted to its activity. This oncogene addiction is evidenced in glioblastoma, pediatric sarcoma, and others.…
