6/17/2025
The research interests in the Kaya Lab lie in the mechanistic understanding of pathways regulating cellular aging and age-related disease progression. We believe that a strong understanding of biological problems…
6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
6/17/2025
Our research focuses on cancer with a special interest in glioblastoma, the most aggressive tumor type of the brain which to date is still considered a deadly disease. Our lab…
6/17/2025
The overall goal of our research is to understand the fundamental mechanisms by which membranes and dietary lipids regulate cell physiology. By understanding the cell biology of lipids and membranes,…
6/17/2025
Epigenetic changes accompany an individual’s development, aging, and disease. They’re particularly significant markers for cancer’s onset and progression, posing substantial therapeutic challenges. Increasing evidence suggests that DNA replication stress leads…
6/17/2025
1. Wnt and PCP signaling in mechanosensory hair cell polarity. The actin-based hair bundle atop sensory hair cells is the mechanotransduction organelle essential for hearing and balance. A majority of sensorineural…
6/17/2025
Our research investigates the biology of the lipid mediator, sphingosine 1-phosphate (S1P). S1P concentration gradients are known to influence immune cell positioning. Indeed, S1P type 1 receptor agonist drugs are…
6/17/2025
My research lies in the areas of statistical genetics and genetic epidemiology with an emphasis on 1) analysis of genome-wide association studies in the multi-ethnic cohort studies, 2) gene-based analysis…
6/17/2025
Within cells there exists a fine balance between survival and death. One of the earliest steps in the development of cancer is the ability of a cell to escape death.…
6/17/2025
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing…
