6/17/2025
1) Seizures as brain explorers: A few thousand neurons acting together can generate a seizure, but it travels far from its origin, generating convulsive and dystonic movements, triggering and erasing…
9/18/2025
My research program at the University of Virginia (UVA) investigates how the heart communicates with other organs to regulate systemic metabolism, and how these pathways can be targeted to treat…
6/17/2025
Matt's research group studies fundamental and applied aspects of mammalian cell signaling and receptor trafficking processes. Signaling and cell phenotype regulation by the epidermal growth factor receptor (EGFR) and the…
6/17/2025
Targeted therapy: by serendipity, we identified a novel oncogene, and found that multiple cancers are addicted to its activity. This oncogene addiction is evidenced in glioblastoma, pediatric sarcoma, and others.…
6/17/2025
6/17/2025
6/17/2025
I have been interested in understanding the regulation and misregulation of retinal structures and functions during normal development and in diseased conditions since my PhD study. I started my own…
6/17/2025
1. Wnt and PCP signaling in mechanosensory hair cell polarity. The actin-based hair bundle atop sensory hair cells is the mechanotransduction organelle essential for hearing and balance. A majority of sensorineural…
6/17/2025
UNLEASH: We work on cytokine control of memory lymphocytes, with a particular interest in the molecular regulators of vaccination and pathological antibodies in different disease states. Experimentally, we use i) mouse…
