Publications / News

1. Chen X, Wang S, Torres M, Hao S, Sun S, Qi L. SEL1L-HRD1 ERAD-autophagy interplay maintains mitochondrial homeostasis in brown adipocytes. Proc Natl Acad Sci U S A. 2026 Mar 24;123(12):e2529914123. doi: 10.1073/pnas.2529914123.
2. Qian W, Wei X, Barros AJ, Ye X, Zhang H, Yu Q, Young SP, Yeatts EV, Park Y, Li C, Hao S, Almeida-Santos G, Tang J, Narasimhan H, Kirk NA, Molinary V, Li Y, Li L, Desai BN, Chen P, Park KS, Zhou AX, Sturek JM, Chen W, Cheon IS, Sun J. Respiratory viral infections prime accelerated lung cancer growth. Cell. 2026 May 14;189(10):2845-2856.e20. doi: 10.1016/j.cell.2026.02.013.
3. Yamaguchi M, Gyarmati G, McLaughlin L, Yamaguchi H, Smith JP, Almeida LF, Matsuoka D, Martini AG, Wilmsen SM, Hao S, Tainaka K, Medrano S, Jain S, Peti-Peterdi J, Sequeira-Lopez MLS, Gomez RA. Renin cells orchestrate a neuro-endocrine microenvironment of the kidney arterial tree in health and disease. JCI Insight. 2026 Jul 16;11(16):e197709. doi: 10.1172/jci.insight.197709
4. Fu SH, Park C, Shah NA, Limerick A, Powers EW, Mann CB, Hyun EM, Zhang Y, Brautigan DL, Hao S, Abounader R, Fu Z. Use of Small-Molecule Inhibitors of CILK1 and AURKA as Cilia-Promoting Drugs to Decelerate Medulloblastoma Cell Replication. Biomedicines. 2026 Jan 24;14(2):265. doi: 10.3390/biomedicines14020265.
5. Genetta TL, Perez-Medero JD, Jang H, Zhang T, Hussain BA, Larner JM. ZEB1 Promotes Alternate Lengthening of Telomeres at Multiple Levels. Cancers (Basel). 2026 Feb 3;18(3):499. doi: 10.3390/cancers18030499. PMID: 41681971; PMCID: PMC12897190.
6. Osuru HP, Atluri N, Le T, Park J, Jedrusiak M, Dulko E, Illendula M, Lunardi N. Epigenetically driven impairment of BDNF-ARC signaling contributes to circadian and cognitive disarray in a mouse model of postoperative delirium. Alzheimers Dement. 2026 Jun;22(6):e71556. doi: 10.1002/alz.71556. PMID: 42298296; PMCID: PMC13269003.
7. Li S, Park J, Phan TM, Caprara GA, Sittipongpittaya N, Sheynkman GM, Peng AW, Egelman EH, Bird JE, Shin JB. Tonotopic specialization of MYO7A isoforms in auditory hair cells. Nat Commun. 2026 Jun 3;17(1):7142. doi: 10.1038/s41467-026-73220-y. PMID: 42236700; PMCID: PMC13396587.
8. Li S, Jun S, Kim YR, Gogineni A, Lee F, Kim CH, Kim UK, Peng AW, Shin JB. A regulatory axis for tonotopic MYO7A expression in cochlear hair cells. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2519742123. doi: 10.1073/pnas.2519742123. Epub 2026 Apr 7. PMID: 41945437; PMCID: PMC13079962.

2025

Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae; Jie Sun
https://pubmed.ncbi.nlm.nih.gov/40048515/

Toxoplasma gondii infection supports the infiltration of T cells into brain tumors; Yen Nguyen
https://pmc.ncbi.nlm.nih.gov/articles/PMC11318612

T-type calcium channels regulate medulloblastoma and can be targeted for therapy. Collin Dube
https://pubmed.ncbi.nlm.nih.gov/39961940/

Carboxyl Terminal Modulator Protein Induces Cell Senescence and Is Upregulated With Aging by Zic2 in Rats; Zhiyi Zuo
https://pubmed.ncbi.nlm.nih.gov/39888066/

Human disease variants of KATNIP fail to support CILK1 activation and control of primary cilia. Evan Carpenter
https://pubmed.ncbi.nlm.nih.gov/40621737/

Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD; Zhenfeng Song
https://pubmed.ncbi.nlm.nih.gov/39455574/

SEL1L Regulates ER Homeostasis in Sertoli Cells but Is Dispensable for Their Function; Shengyi Sun
https://pubmed.ncbi.nlm.nih.gov/40498659/

The ER-associated degradation adaptor SEL1L is dispensable for ER homeostasis and the differentiation of spermatogenic cells; Nusrat Tushi
https://pubmed.ncbi.nlm.nih.gov/40412517/

Auditory fear memory retrieval requires BLA-LS and LS-VMH circuitries via GABAergic and dopaminergic neurons; Miao Chen
https://pubmed.ncbi.nlm.nih.gov/40055468/

Conjugation of IL-33 to Microporous Annealed Particle Scaffolds Enhances Type 2-Like Immune Responses In Vitro and In Vivo; Donald Griffin 
https://pubmed.ncbi.nlm.nih.gov/38648258/

Microporous Annealed Particle (MAP) Scaffold Pore Size Influences Mesenchymal Stem Cell Metabolism and Proliferation Without Changing CD73, CD90, and CD105 Expression Over Two Weeks; Blaise N Pfaff
https://pubmed.ncbi.nlm.nih.gov/37955859/

Immune cell activation produces locally scrambled foci of plasma membrane lipids; Kandice Levental
https://pubmed.ncbi.nlm.nih.gov/40351229/

2024

Endosomal fusion of pH-dependent enveloped viruses requires ion channel TRPM7; Bimal Desai
https://pmc.ncbi.nlm.nih.gov/articles/PMC11445543/

Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress; Brant Isakson
https://pubmed.ncbi.nlm.nih.gov/38289985/

Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth; Collin Dube
https://pubmed.ncbi.nlm.nih.gov/39229003/

An Epilepsy-Associated CILK1 Variant Compromises KATNIP Regulation and Impairs Primary Cilia and Hedgehog Signaling; Ana Limerick
https://pubmed.ncbi.nlm.nih.gov/39120290/

A Novel Mutation in LXRα Uncovers a Role for Cholesterol Sensing in Limiting Metabolic Dysfunction-Associated Steatohepatitis (MASH); Alexis Clark
https://pubmed.ncbi.nlm.nih.gov/38798597/

Multisite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox with diverse applications in vertebrate model systems; William Gillespie
https://pubmed.ncbi.nlm.nih.gov/39026881/

Transformation of the Kidney into a Pathological Neuro-Immune-Endocrine Organ; Manako Yamaguchi
https://pubmed.ncbi.nlm.nih.gov/39351666/

Bone marrow stromal cell antigen-1 deficiency protects from acute kidney injury; Mark Okusa https://pubmed.ncbi.nlm.nih.gov/37969103/ 

An efficient inducible model for the control of gene expression in renin cells; Ariel Gomez
https://pubmed.ncbi.nlm.nih.gov/38991008/

Novel Mouse Model of Myocardial Infarction, Plaque Rupture, and Stroke Shows Improved Survival With Myeloperoxidase Inhibition; Gary Owens
https://pubmed.ncbi.nlm.nih.gov/38881440/

Protocol for integrating tissue clearing and light-sheet imaging to analyze cancer initiation in mosaic analysis with double markers mouse models; Hui Zong
https://pubmed.ncbi.nlm.nih.gov/38796848/

Anatomical substrates of Rapid Eye Movement sleep rebound in a rodent model of post-sevoflurane sleep disruption. Nadia Lunardi
https://pubmed.ncbi.nlm.nih.gov/38157434/

IL-1β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice; Gary Owens
https://pubmed.ncbi.nlm.nih.gov/38695167/

Coupling of protein condensates to ordered lipid domains determines functional membrane organization; Hong-Yin Wang
https://pubmed.ncbi.nlm.nih.gov/37126554/

Endothelial-adipocyte Cx43 Mediated Gap Junctions Can Regulate Adiposity; Melissa Luse
https://pubmed.ncbi.nlm.nih.gov/38984993/

2023
Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain; Jung-Bum Shin
https://pubmed.ncbi.nlm.nih.gov/37294664/

Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging; Bimal N. Desai
https://pubmed.ncbi.nlm.nih.gov/37277641/

miR-3174 Is a New Tumor Suppressor MicroRNA That Inhibits Several Tumor-Promoting Genes in Glioblastoma; Roger Abounader
https://pubmed.ncbi.nlm.nih.gov/37298284/

The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia. Jacob Turner
https://pubmed.ncbi.nlm.nih.gov/37665596/

IL-1β inhibition partially negates the beneficial effects of diet-induced lipid lowering. Santosh Karnewar
https://pubmed.ncbi.nlm.nih.gov/37873280/

Endoplasmic reticulum stress-activated neuronal and microglial autophagy contributes to postoperative cognitive dysfunction in neonatal rats. Hui Zhang
https://pubmed.ncbi.nlm.nih.gov/36717512/

Highly-conserved regulatory activity of the ANR family in the virulence of diarrheagenic bacteria through interaction with master and global regulators; James P Nataro
https://pubmed.ncbi.nlm.nih.gov/37120613/

Coupling of protein condensates to ordered lipid domains determines functional membrane organization; Ilya Levental
https://pubmed.ncbi.nlm.nih.gov/37126554/

Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells; Chunsong Yang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10108886/

Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1; Brant Isakson
https://pubmed.ncbi.nlm.nih.gov/37014698/

Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation; Craig Kent
https://pubmed.ncbi.nlm.nih.gov/36923952/

A New Autosomal Myh11-CreERT2 Smooth Muscle Cell Lineage Tracing and Gene Knockout Mouse Model; Rebecca Deaton
https://pubmed.ncbi.nlm.nih.gov/36519470/

2022
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma; Dane T Sessions
https://pubmed.ncbi.nlm.nih.gov/36516772/

Modulation of Primary Cilia by Alvocidib Inhibition of CILK1; Zheng Fu
https://pubmed.ncbi.nlm.nih.gov/35897693/

Efferocytosis requires periphagosomal Ca2+-signaling and TRPM7-mediated electrical activity; Bimal N. Desai
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9184625/

Dichotomous roles of smooth muscle cell–derived MCP1 (monocyte chemoattractant protein 1) in development of atherosclerosis; Gary Owens
https://pubmed.ncbi.nlm.nih.gov/35735018/

Ecdysone exerts biphasic control of regenerative signaling, coordinating the completion of regeneration with developmental progression; Adrian Halme
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812538/

Delivery of Dissociated Islets Cells within Microporous Annealed Particle Scaffold to Treat Type 1 Diabetes; Coleen Roosa
https://pmc.ncbi.nlm.nih.gov/articles/PMC9674036/