6/17/2025
Ongoing work in my laboratory focuses on the role of an alternative splicing factor, the RNA helicase DDX39B, known to immunologists as BAT1, on immunity and autoimmunity. The connection to…
6/17/2025
Multiple Sclerosis is a currently incurable autoimmune disease that affects 400,000 Americans and millions worldwide. The disease is characterized by destruction of myelin, the protective coat that wraps neuronal axons…
6/17/2025
The goal of my research is to understand the mechanistic underpinnings of the cell signaling network that contribute to cancer progression and resistance to therapy. My laboratory is currently focused…
6/17/2025
The lab has two related areas of interest: 1) development of red cells and platelets within bone marrow precursors, and 2) the effects of iron deprivation on red cell and…
6/17/2025
Biological processes ranging from gene transcription to behavior oscillate and are synchronized to the 24-hour day/night cycle. Mammalian circadian rhythms, orchestrated by the hypothalamic suprachiasmatic nucleus (SCN) allow appropriately timed…
6/17/2025
My research is focused on elucidating the immunoregulatory mechanism by Hepatitis C virus (HCV). HCV is a global health concern causing severe liver disease such as fibrosis, cirrhosis and hepatocellular…
6/17/2025
Toxoplasma gondii is an intracellular, protozoan parasite that infects approximately one-third of the world population. The parasite can be acquired congenitally or in adults, through the ingestion of contaminated food…
6/17/2025
As Paleolithic hunter gatherers, the human diet was relatively low in fats and simple carbohydrates. Technological advances, beginning with the agricultural revolution 12,000 years ago and culminating with the mechanization…
6/17/2025
Our laboratory is specifically interested in the regulation of vascular cell commitment, differentiation and cell cycle progression, and defining signaling pathways that modulate these processes. We also aim to understand…
6/17/2025
Diagnostic ultrasound - image processing, quantification Molecular imaging using ultrasound Catheter-based ultrasound Ultrasound-based drug/gene delivery Ultrasound image guided therapy
