6/17/2025
The etiology of many cardiovascular diseases can be traced to the microcirculation, which is the primary focus of the Isakson lab. For example, high blood pressure as well as strokes…
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
6/17/2025
Our research focuses on several key areas that drive our scientific interests and contribute to the understanding and treatment of neurodegenerative diseases. These areas include: 1. Investigation of RNA modifications and…
6/17/2025
My lab investigates the molecular mechanisms that control how cells manage protein biogenesis and adapt to stress, with broad implications for human disease. 1. Cell Dormancy – We study the…
6/17/2025
1) Seizures as brain explorers: A few thousand neurons acting together can generate a seizure, but it travels far from its origin, generating convulsive and dystonic movements, triggering and erasing…
6/17/2025
Introduction: Mitochondria are often pictured in biology texts as static, individual organelles, when in reality they form highly dynamic and mobile networks constantly undergoing fusion and fission. Research in the last…
6/17/2025
Advancement in the design of imaging agents has many far-reaching implications for the future directions of molecular imaging and radiological sciences including the following: (1) The early detection of disease…
6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
6/17/2025
Ultrasound imaging is a widespread and inexpensive non-invasive diagnostic technique. Ultrasound contrast agents offer a flexible platform that can be used for diagnostic imaging as a blood pool marker (tissue…
6/17/2025
Cardiovascular magnetic resonance imaging is a powerful technology that has evolved into a comprehensive imaging approach to cardiovascular disease. A major focus of our work is on developing clinical applications…
