6/17/2025
Living cells and tissues adapt to their environment by altering structure, gene and protein expression, and biochemical functions. For example, endothelial cells lining the artery wall at the blood tissue…
6/17/2025
The etiology of many cardiovascular diseases can be traced to the microcirculation, which is the primary focus of the Isakson lab. For example, high blood pressure as well as strokes…
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
6/17/2025
6/17/2025
Advancement in the design of imaging agents has many far-reaching implications for the future directions of molecular imaging and radiological sciences including the following: (1) The early detection of disease…
6/17/2025
Kelsey Kubelick's research group, K2 BioImaging Collective, leverages light, sound, nanoconstruct design, and cellular engineering strategies to develop advanced theranostic imaging techniques, with a particular interest in ultrasound and photoacoustic (PA)…
6/17/2025
WE USE FROGS TO STUDY DEVELOPMENT, DISEASE, AND REGENERATION PRECISION MEDICINE OF BIRTH DEFECTS Every parent that loses their baby to a birth defect wants to know why and if it will…
6/17/2025
SERCA2a [the Ca-ATPase of sarcoplasmic reticulum (SR) of cardiac muscle] plays a central role in intracellular calcium dynamics and thus in the contractility of the heart. The SR regulates the…
6/17/2025
Our laboratory is developing applications of molecular mechanics to the challenges of targeted drug and gene delivery. To increase specificity and reduce toxic side effects, we are incorporating leukocyte adhesion…
6/21/2025
Our laboratory is interested in the cellular mechanisms of neuronal vulnerability associated with stroke. A multidisciplinary approach has been undertaken to elucidate how neurons are destabilized during ischemia and what…
