6/17/2025
Targeted therapy: by serendipity, we identified a novel oncogene, and found that multiple cancers are addicted to its activity. This oncogene addiction is evidenced in glioblastoma, pediatric sarcoma, and others.…
6/17/2025
The focus of my research has been the pharmacology and physiology of adenosine receptors. Various agonists and antagonists of adenosine receptors have therapeutic uses or potential for the treatment of…
6/17/2025
How do the regulatory networks that maintain gene expression programs change in response to stimuli and in disease states? The primary goal of my research program is to address this…
6/17/2025
My laboratory aims to explore the physiological role of endoplasmic reticulum (ER) homeostasis (with a special focus on ER-associated degradation, ERAD) in the context of human diseases. We use genetic,…
6/17/2025
All eukaryotic cells divide by assembling a microtubule-based spindle machinery that equally segregates chromosomes between daughter cells. The faithful segregation of chromosomes during cell division is essential as errors in…
6/17/2025
Our team studies how neurons assemble into circuits and how those circuits adapt to the environment. We use state-of-the-art neuroscience tools in the rodent visual system to ultimately understand how learning…
6/17/2025
My laboratory studies the biological conflict between bacteria and the viruses that infect them: bacteriophages (phages). Bacteriophages are the most abundant entity on the planet, and are crucial for controlling…
6/17/2025
My research is aimed towards understanding the role of microtubules, motors and components of membrane domains in Clathrin Independent Endocytosis (CIE) of growth factor receptors and other cargoes including bacterial…
6/17/2025
Our research focuses on the molecular mechanisms of mitochondrial calcium transport and signaling. We aim to understand how these mitochondrial processes contribute to cardiovascular and neuronal physiology, as well as…
6/17/2025
We forge collaborative efforts at the dynamic intersection of biology, chemistry, and medicine, propelling forward the boundaries of scientific exploration. Our work revolves around the development of cutting-edge imaging tools,…
