6/17/2025
The design of self-assembling nanomaterials stands as one of the great challenges in modern molecular science. The DuBay group employs theoretical and computational tools to address this challenge through investigations…
6/17/2025
Our research is focused on the structure and function of macromolecular assemblies, using the techniques of electron cryo-microscopy and three-dimensional reconstruction. Historically, we have been working in two different areas:…
6/17/2025
6/17/2025
We develop nanoscale imaging methods for 3D single-molecule localization in intact bacterial cells. Our two primary research objectives are: 1. Development of 3D super-resolution imaging methods, including instrument design, sample preparation,…
6/17/2025
We aim to understand how eukaryotic cells control chromatin structure. Knowledge of chromatin-structure at the level of its nucleosome subunits inside cells will give far-reaching mechanistic insight into gene regulation,…
6/17/2025
My lab investigates the molecular mechanisms that control how cells manage protein biogenesis and adapt to stress, with broad implications for human disease. 1. Cell Dormancy – We study the…
6/17/2025
Pathogenesis of Kaposi's Sarcoma-Associated Herpesvirus Kaposi's sarcoma (KS) remains one of the two most common AIDS-associated malignancies and is caused by the human herpesvirus, KSHV, first discovered in 1994. Nevertheless,…
6/17/2025
The goal of our research is to learn the cellular, molecular and biomechanical mechanisms underlying morphogenetic movements during embryogenesis. One of the fundamental problems in developmental biology is determining what…
6/17/2025
Research Description One of the major goals of my research program is to understand the role of membrane microdomains such as lipid rafts and caveolae in health and disease. We address…
