6/17/2025
Genetics of complex disease Common diseases, such as osteoporosis, impart significant societal health burdens. These diseases are, in part, regulated by genetic determinants and understanding their genetic basis is critical to…
6/17/2025
6/17/2025
Our interests focus on developing gene therapy for treating and preventing cardio-vascular disease. An interdisciplinary approach is used to integrate recent technical advances with gene therapy research. In particular, cutting-edge…
6/17/2025
We develop nanoscale imaging methods for 3D single-molecule localization in intact bacterial cells. Our two primary research objectives are: 1. Development of 3D super-resolution imaging methods, including instrument design, sample preparation,…
6/17/2025
The Guo lab studies vascular wall remodeling and retinal degeneration, with a focus on the role of histone-code readers and writers in driving cell phenotypic transitions. We aim to uncover…
6/17/2025
As Paleolithic hunter gatherers, the human diet was relatively low in fats and simple carbohydrates. Technological advances, beginning with the agricultural revolution 12,000 years ago and culminating with the mechanization…
6/17/2025
The etiology of many cardiovascular diseases can be traced to the microcirculation, which is the primary focus of the Isakson lab. For example, high blood pressure as well as strokes…
6/17/2025
Our research focuses on several key areas that drive our scientific interests and contribute to the understanding and treatment of neurodegenerative diseases. These areas include: 1. Investigation of RNA modifications and…
6/17/2025
1) Seizures as brain explorers: A few thousand neurons acting together can generate a seizure, but it travels far from its origin, generating convulsive and dystonic movements, triggering and erasing…
