Mami Taniuchi, PhD

A Phase II Evaluation of the Safety and Protective Efficacy of the Live Attenuated Tetravalent Dengue Vaccine TetraVax-DV with Challenge by the Recombinant DENV-2 Virus in a Dengue Endemic Population. UVA sub: My role is to develop and validate PCR assays to detect Dengue virus for the primary endpoints of the parent clinical trial. Our team will extract RNA from sera samples from the study and then test all the sera samples from the vaccine study for DENV-2 Virus.

Passive Environmental Sampler for Polioviruses II (supplement). During the polio endgame and once the world is certified polio-free, environmental surveillance (ES) will be increasingly important to monitor for silent circulation of polio and to ensure that polio is eradicated. For this investment, we are developing a new generation passive sampler for capturing poliovirus and rapid, sensitive methods to screen the ES samples for polio at the site of collection or a nearby low-resourced lab to screen the ES samples.

Multipathogen Environmental Surveillance in Dhaka. Building on our successful surveillance of SARS-CoV-2 in sewage, we are expanding the sewage surveillance to include other pathogens of public health interest in Dhaka, Bangladesh, and developing multipathogen transmission models to estimate community transmission of infectious diseases. The new surveillance will focus on other vaccine preventable infectious diseases of public health interest like influenza, measles, cholera, and RSV.

Household Transmission of Cryptosporidium. UVA sub will focus on developing a customized enteric TaqMan Array Card and testing diarrheal samples from this study to determine the etiology of diarrhea.

Passive Environmental Sampler for Polioviruses. Development of a new device to capture poliovirus and new CRISPR-based diagnostics for poliovirus. Current methods used for the detection of poliovirus from an environmental sample is culture-based and takes 3 weeks. The main objective is to develop a sensitive method to directly detect the poliovirus from wastewater without culture for surveillance in real-time.

Source attribution and transmission dynamics of Campylobacter and Shigella using culture-independent molecular methods in an urban slum in Dhaka, Bangladesh. Investigation of the sources and routes of transmission for Shigella and Campylobacter, two important causes of diarrhea in young children, in an urban low-resource setting in Dhaka, Bangladesh. Development of mathematical models to determine the relative importance of person-to-person and environmental transmission pathways to define the pathogen-specific household and environmental pathways of highest relevance for these two pathogens.

Surveillance for enteric pathogens in sewage in Karachi (Karachi enteric pathogen surveillance: KEPS). Development of molecular tools for clinical and sewage surveillances for multipathogens, including poliovirus, SARS-CoV-2, and other vaccine-preventable diseases in Karachi, Pakistan.

TaqMan Array Card method for polio environmental surveillance. Develop novel tools to detect polio and antimicrobial resistance genes from the environmental samples for the polio endgame—application of this tool to environmental surveillance for poliovirus post-immunization campaigns in Bangladesh and India.

• National Institute of Health U01AI134582 (A Phase II Evaluation of the Safety and Protective Efficacy of the Live Attenuated Tetravalent Dengue Vaccine TetraVax-DV with Challenge by the Recombinant DENV-2 Virus in a Dengue Endemic Population) (ends July 2024)
• Bill & Melinda Gates Foundation INV-050980 (Passive Environmental Sampler for Polioviruses II (supplement))
• Bill & Melinda Gates Foundation INV-058557 (Multipathogen Environmental Surveillance in Dhaka)
• NIH 5R01 AI 146123-04 (Household Transmission of Cryptosporidium) (ends June 2024)
• Bill and Melinda Gates Foundation INV-050980 (Passive Environmental Sampler for Polioviruses)
• U.S. NIH Fogarty International Center 1R01TW012183-01 (Source attribution and transmission dynamics of Campylobacter and Shigella using culture-independent molecular methods in an urban slum in Dhaka, Bangladesh)
• Bill and Melinda Gates Foundation INV-025308 (Surveillance for enteric pathogens in sewage in Karachi (Karachi enteric pathogen surveillance: KEPS)) (ends June 2024)

Pub Med

NIH RePORT

2024

• Lee B, Kader MA, Alam M, Dickson DM, Harvey P, Colgate ER, Taniuchi M, Petri WA Jr, Haque R, Kirkpatrick BD. Infant Non-Secretor Histoblood Group Antigen Phenotype Reduces Susceptibility to Both Symptomatic and Asymptomatic Rotavirus Infection. Pathogens. 2024 Mar 4;13(3):223. doi: 10.3390/pathogens13030223. PMID: 38535566; PMCID: PMC10974866. Cited 0 times.
• Gerety MK, Kim DK, Carpenter RM, Ma JZ, Chisholm C, Taniuchi M, Islam MO, Pholwat S, Platts-Mills JA, Siraj MS, Billah SM, Haque R, Petri WA Jr. Systemic inflammation, enteropathogenic E. Coli, and micronutrient insufficiencies in the first trimester as possible predictors of preterm birth in rural Bangladesh: a prospective study. BMC Pregnancy Childbirth. 2024 Jan 24;24(1):82. doi: 10.1186/s12884-024-06266-9. PMID: 38267943. Cited 0 times.

2023

• Cohen A, Vikesland P, Pruden A, Krometis LA, Lee LM, Darling A, Yancey M, Helmick M, Singh R, Gonzalez R, Meit M, Degen M, Taniuchi M. Making waves: The benefits and challenges of responsibly implementing wastewater-based surveillance for rural communities. Water Res. 2024 Feb 15;250:121095. doi: 10.1016/j.watres.2023.121095. Epub 2023 Dec 30. PMID: 38181645. Cited 0 times.
• Ciszewski J, Taniuchi M, Lee B, Colgate ER, Platts-Mills JA, Haque R, Zaman K, Lopman B, Petri WA Jr, Kirkpatrick BD, Rogawski McQuade ET. Differences in Rotavirus Shedding and Duration by Infant Oral Rotavirus Vaccination Status in Dhaka, Bangladesh 2011 – 2014. J Infect Dis. 2023 Nov 29:jiad502. doi: 10.1093/infdis/jiad502. Epub ahead of print. PMID: 38019181. Cited 1 time.
• Shaw AG, Troman C, Akello JO, O’Reilly KM, Gauld J, Grow S, Grassly N, Steele D, Blazes D, Kumar S; Environmental Surveillance Working Group. Defining a research agenda for environmental wastewater surveillance of pathogens. Nat Med. 2023 Aug 3. doi: 10.1038/s41591-023-02457-7. Epub ahead of print. PMID: 37537374. Cited 0 times.
• Wettstone EG, Islam MO, Hughlett L, Reagen C, Shirin T, Rahman M, Hosan K, Hoque MR, Brennhofer SA, Rogawski McQuade ET, Mira Y, von Tobel L, Haque R, Taniuchi M, Blake IM. Interactive SARS-CoV-2 dashboard for real-time geospatial visualisation of sewage and clinical surveillance data from Dhaka, Bangladesh: a tool for public health situational awareness. BMJ Glob Health. 2023 Aug;8(8):e012921. doi: 10.1136/bmjgh-2023-012921. PMID: 37620099; PMCID: PMC10450138. Cited 0 times.’
• Garbern SC, Islam MT, Islam K, Ahmed SM, Brintz BJ, Khan AI, Taniuchi M, Platts-Mills JA, Qadri F, Leung DT. Derivation and External Validation of a Clinical Prediction Model for Viral Diarrhea Etiology in Bangladesh. Open Forum Infect Dis. 2023 May 29;10(7):ofad295. doi: 10.1093/ofid/ofad295. PMID: 37404954; PMCID: PMC10316693. Cited 0 times.
• Rogawski McQuade ET, Blake IM, Brennhofer SA, Islam MO, Sony SSS, Rahman T, Bhuiyan MH, Resha SK, Wettstone EG, Hughlett L, Reagan C, Elwood SE, Mira Y, Mahmud AS, Hosan K, Hoque MR, Alam MM, Rahman M, Shirin T, Haque R, Taniuchi M*. Real-time sewage surveillance for SARS-CoV-2 in Dhaka, Bangladesh versus clinical COVID-19 surveillance: a longitudinal environmental surveillance study (December, 2019-December, 2021). Lancet Microbe. 2023 Apr 3:S2666-5247(23)00010-1. doi: 10.1016/S2666-5247(23)00010-1. Epub ahead of print. PMID: 37023782; PMCID: PMC10069819. Cited 6 times.

2022

• Cohen A, Rasheduzzaman M, Darling A, Krometis LA, Edwards M, Brown T, Ahmed T, Wettstone E, Pholwat S, Taniuchi M, Rogawski McQuade ET. Bottled and Well Water Quality in a Small Central Appalachian Community: Household-Level Analysis of Enteric Pathogens, Inorganic Chemicals, and Health Outcomes in Rural Southwest Virginia. Int J Environ Res Public Health. 2022 Jul 15;19(14):8610. doi: 10.3390/ijerph19148610. PMID: 35886462; PMCID: PMC9319903. Cited 3 times.
• Obiero CW, Gumbi W, Mwakio S, Mwangudzah H, Seale AC, Taniuchi M, Liu J, Houpt E, Berkley JA. Detection of pathogens associated with early-onset neonatal sepsis in cord blood at birth using quantitative PCR. Wellcome Open Res. 2022 May 11;7:3. doi: 10.12688/wellcomeopenres.17386.2. PMID: 35600002; PMCID: PMC9114825. Cited 3 times.
• Garbern SC, Nelson EJ, Nasrin S, Keita AM, Brintz BJ, Gainey M, Badji H, Nasrin D, Howard J, Taniuchi M, Platts-Mills JA, Kotloff KL, Haque R, Levine AC, Sow SO, Alam NH, Leung DT. External validation of a mobile clinical decision support system for diarrhea etiology prediction in children: a multicenter study in Bangladesh and Mali. Elife. 2022 Feb 9;11:e72294. doi: 10.7554/eLife.72294. Epub ahead of print. PMID: 35137684. Cited 2 times.
• Colston JM, Taniuchi M, Ahmed T, Ferdousi T, Kabir F, Mduma E, Nshama R, Iqbal NT, Haque R, Ahmed T, Ali Bhutta Z, Kosek MN, Platts-Mills JA. Intestinal Colonization With Bifidobacterium longum Subspecies Is Associated With Length at Birth, Exclusive Breastfeeding, and Decreased Risk of Enteric Virus Infections, but Not With Histo-Blood Group Antigens, Oral Vaccine Response or Later Growth in Three Birth Cohorts. Front Pediatr. 2022 Feb 16;10:804798. doi: 10.3389/fped.2022.804798. PMID: 35252058; PMCID: PMC8888871. Cited 7 times.
• Donowitz JR, Pu Z, Lin Y, Alam M, Ferdous T, Shama T, Taniuchi M, Islam MO, Kabir M, Nayak U, Faruque ASG, Haque R, Ma JZ, Petri WA Jr. Small Intestine Bacterial Overgrowth in Bangladeshi Infants Is Associated With Growth Stunting in a Longitudinal Cohort. Am J Gastroenterol. 2022 Jan 1;117(1):167-175. doi: 10.14309/ajg.0000000000001535. PMID: 34693912; PMCID: PMC8715995. Cited 8 times.

2021

• Famulare M, Wong W, Haque R, Platts-Mills JA, Saha P, Aziz AB, Ahmed T, Islam MO, Uddin MJ, Bandyopadhyay AS, Yunus M, Zaman K, Taniuchi M*. Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission. PLoS Comput Biol. 2021 Dec 21;17(12):e1009690. doi: 10.1371/journal.pcbi.1009690. PMID: 34932560; PMCID: PMC8726461. Cited 4 times.
• Pholwat S, Liu J, Taniuchi M, Haque R, Alam MM, Faruque ASG, Ferdous T, Ara R, Platts-Mills JA, Houpt ER. Use of Molecular Methods To Detect Shigella and Infer Phenotypic Resistance in a Shigella Treatment Study. J Clin Microbiol. 2022 Jan 19;60(1):e0177421. doi: 10.1128/JCM.01774-21. Epub 2021 Oct 20. PMID: 34669456; PMCID: PMC8769. Cited 3 times.
• Donowitz JR, Drew J, Taniuchi M, Platts-Mills JA, Alam M, Ferdous T, Shama T, Islam MO, Kabir M, Nayak U, Haque R, Petri WA. Diarrheal Pathogens Associated with Growth and Neurodevelopment. Clin Infect Dis. 2021 Jan 5:ciaa1938. doi: 10.1093/cid/ciaa1938. Epub ahead of print. PMID: 33399861. Cited 13 times.

2020

• Valesano AL, Taniuchi M, Fitzsimmons WJ, Islam MO, Ahmed T, Zaman K, Haque R, Wong W, Famulare M, Lauring AS. The Early Evolution of Oral Poliovirus Vaccine Is Shaped by Strong Positive Selection and Tight Transmission Bottlenecks. Cell Host Microbe. 2021 Jan 13;29(1):32-43.e4. doi: 10.1016/j.chom.2020.10.011. Epub 2020 Nov 18. PMID: 33212020. Cited 15 times.
• Liu J, Pholwat S, Zhang J, Taniuchi M, Haque R, Alam M, Ochieng JB, Jones JA, Platts-Mills JA, Tennant SM, Houpt E. Evaluation of Molecular Serotyping Assays for Shigella flexneri Directly on Stool Samples. J Clin Microbiol. 2020 Nov 25:JCM.02455-20. doi: 10.1128/JCM.02455-20. Epub ahead of print. PMID: 33239379. Cited 11 times.
• Pavlinac PB, Platts-Mills JA, Tickell KD, Liu J, Juma J, Kabir F, Nkeze J, Okoi C, Operario DJ, Uddin MJ, Ahmed S, Alonso PL, Antonio M, Becker SM, Breiman RF, Faruque ASG, Fields B, Gratz J, Haque R, Hossain A, Hossain MJ, Jarju S, Qamar F, Iqbal NT, Kwambana B, Mandomando I, McMurry TL, Ochieng C, Ochieng JB, Ochieng M, Onyango C, Panchalingam S, Kalam A, Aziz F, Qureshi S, Ramamurthy T, Roberts JH, Saha D, Sow SO, Stroup SE, Sur D, Tamboura B, Taniuchi M, Tennant SM, Roose A, Toema D, Wu Y, Zaidi A, Nataro JP, Levine MM, Houpt ER, Kotloff KL. The clinical presentation of culture-positive and culture-negative, qPCR-attributable shigellosis in the Global Enteric Multicenter Study and derivation of a Shigella severity score: implications for pediatric Shigella vaccine trials. Clin Infect Dis. 2020 Oct 12:ciaa1545. doi: 10.1093/cid/ciaa1545. Epub ahead of print. PMID: 33044509. Cited 9 times.
• Goddard FGB, Ban R, Barr DB, Brown J, Cannon J, Colford JM Jr, Eisenberg JNS, Ercumen A, Petach H, Freeman MC, Levy K, Luby SP, Moe C, Pickering AJ, Sarnat JA, Stewart J, Thomas E, Taniuchi M, Clasen T. Measuring Environmental Exposure to Enteric Pathogens in Low-Income Settings: Review and Recommendations of an Interdisciplinary Working Group. Environ Sci Technol. 2020 Oct 6;54(19):11673-11691. doi: 10.1021/acs.est.0c02421. Epub 2020 Sep 9. PMID: 32813503; PMCID: PMC7547864. Cited 29 times.
• Pedrosa de Macena LDG, Castiglia Feitosa R, Vieira CB, Araújo IT, Taniuchi M, Miagostovich MP. Microbiological assessment of an urban lagoon system in the coastal zone of Rio de Janeiro, Brazil. Environ Sci Pollut Res Int. 2021 Jan;28(1):1170-1180. doi: 10.1007/s11356-020-10479-8. Epub 2020 Aug 24. PMID: 32839906. Cited 10 times.
• Grembi JA, Lin A, Karim MA, Islam MO, Miah R, Arnold BF, McQuade ETR, Ali S, Rahman MZ, Hussain Z, Shoab AK, Famida SL, Hossen MS, Mutsuddi P, Rahman M, Unicomb L, Haque R, Taniuchi M, Liu J, Platts-Mills JA, Holmes SP, Stewart CP, Benjamin-Chung J, Colford JM, Houpt ER, Luby SP. Effect of water, sanitation, handwashing and nutrition interventions on enteropathogens in children 14 months old: a cluster-randomized controlled trial in rural Bangladesh. J Infect Dis. 2020 Aug 29:jiaa549. doi: 10.1093/infdis/jiaa549. Epub ahead of print. PMID: 32861214. Cited 11 times.
• Taniuchi M, Islam K, Sayeed MA, Platts-Mills JA, Islam MT, Khabir MIU, Rahman M, Khan ZH, Begum YA, Khanam F, Islam Khan A, Liu J, Houpt ER, Qadri F. Etiology of diarrhea requiring hospitalization in Bangladesh by quantitative PCR, 2014-2018. Clin Infect Dis. 2020 Jun 27:ciaa840. doi: 10.1093/cid/ciaa840. Epub ahead of print. PMID: 32592580. Cited 8 times.
• Pholwat S, Pongpan T, Chinli R, Rogawski McQuade ET, Thaipisuttikul I, Ratanakorn P, Liu J, Taniuchi M, Houpt ER, Foongladda S. Antimicrobial Resistance in Swine Fecal Specimens Across Different Farm Management Systems. Front Microbiol. 2020 Jun 17;11:1238. doi: 10.3389/fmicb.2020.01238. PMID: 32625181; PMCID: PMC7311580. Cited 16 times.
• Houpt ER, Ferdous T, Ara R, Ibrahim M, Alam MM, Kabir M, Platts-Mills J, Ahmed T, Faruque ASG, Taniuchi M, Haque R. Clinical outcomes of drug-resistant shigellosis treated with azithromycin in Bangladesh. Clin Infect Dis. 2020 Apr 2:ciaa363. doi: 10.1093/cid/ciaa363. Epub ahead of print. PMID: 32239137. Cited 20 times.

2019

• Church JA, Rogawski McQuade ET, Mutasa K, Taniuchi M, Rukobo S, Govha M, Lee B, Carmolli MP, Chasekwa B, Ntozini R, McNeal MM, Moulton LH, Kirkpatrick BD, Liu J, Houpt ER, Humphrey JH, Platts-Mills JA, Prendergast AJ. Enteropathogens and Rotavirus Vaccine Immunogenicity in a Cluster Randomized Trial of Improved Water, Sanitation and Hygiene in Rural Zimbabwe. Pediatr Infect Dis J. 2019 Dec;38(12):1242-1248. Cited 8 times.
• Lee B, Dickson DM, Alam M, Afreen S, Kader A, Afrin F, Ferdousi T, Damon CF, Gullickson SK, McNeal MM, Bak DM, Tolba M, Carmolli MP, Taniuchi M, Haque R, Kirkpatrick BD. The effect of increased inoculum on oral rotavirus vaccine take among infants in Dhaka, Bangladesh: A double-blind, parallel group, randomized, controlled trial. Vaccine. 2020 Jan 3;38(1):90-99. Cited 9 times.
• Donowitz JR, Parikh HI, Taniuchi M, Gilchrist CA, Haque R, Kirkpatrick BD, Alam M, Kakon SH, Islam BZ, Afreen S, Kabir M, Nayak U, Colgate ER, Carmolli MP, Petri WA Jr. Increased Fecal Lactobacillus Is Associated With a Positive Glucose Hydrogen Breath Test in Bangladeshi Children. Open Forum Infect Dis. 2019 Jun 1;6(7):ofz266. Cited 3 times.
• Pholwat S, Liu J, Taniuchi M, Chinli R, Pongpan T, Thaipisutikul I, Ratanakorn P, Platts-Mills JA, Fleece M, Stroup S, Gratz J, Mduma E, Mujaga B, Walongo T, Nshama R, Kimathi C, Foongladda S, Houpt ER. Genotypic antimicrobial resistance assays for use on E. coli isolates and stool specimens. PLoS One. 2019 May 10;14(5):e0216747. Cited 13 times.

2018

• Rogawski ET, Liu J, Platts-Mills JA, Kabir F, Lertsethtakarn P, Siguas M, Khan SS, Praharaj I, Murei A, Nshama R, Mujaga B, Havt A, Maciel IA, Operario DJ, Taniuchi M, Gratz J, Stroup SE, Roberts JH, Kalam A, Aziz F, Qureshi S, Islam MO, Sakpaisal P, Silapong S, Yori PP, Rajendiran R, Benny B, McGrath M, Seidman JC, Lang D, Gottlieb M, Guerrant RL, Lima AAM, Leite JP, Samie A, Bessong PO, Page N, Bodhidatta L, Mason C, Shrestha S, Kiwelu I, Mduma ER, Iqbal NT, Bhutta ZA, Ahmed T, Haque R, Kang G, Kosek MN, Houpt ER; MAL-ED Network Investigators. Use of quantitative molecular diagnostic methods to investigate the effect of enteropathogen infections on linear growth in children in low-resource settings: longitudinal analysis of results from the MAL-ED cohort study. Lancet Glob Health. 2018 Dec;6(12):e1319-e1328. Cited 202 times.
• Platts-Mills JA, Liu J, Rogawski ET, Kabir F, Lertsethtakarn P, Siguas M, Khan SS, Praharaj I, Murei A, Nshama R, Mujaga B, Havt A, Maciel IA, McMurry TL, Operario DJ, Taniuchi M, Gratz J, Stroup SE, Roberts JH, Kalam A, Aziz F, Qureshi S, Islam MO, Sakpaisal P, Silapong S, Yori PP, Rajendiran R, Benny B, McGrath M, McCormick BJJ, Seidman JC, Lang D, Gottlieb M, Guerrant RL, Lima AAM, Leite JP, Samie A, Bessong PO, Page N, Bodhidatta L, Mason C, Shrestha S, Kiwelu I, Mduma ER, Iqbal NT, Bhutta ZA, Ahmed T, Haque R, Kang G, Kosek MN, Houpt ER; MAL-ED Network Investigators. Use of quantitative molecular diagnostic methods to assess the aetiology, burden, and clinical characteristics of diarrhoea in children in low-resource settings: a reanalysis of the MAL-ED cohort study. Lancet Glob Health. 2018 Dec;6(12):e1309-e1318. Cited 220 times.
• Schnee AE, Haque R, Taniuchi M, Uddin MJ, Alam MM, Liu J, Rogawski ET, Kirkpatrick B, Houpt ER, Petri WA Jr, Platts-Mills JA. Identification of Etiology-Specific Diarrhea Associated With Linear Growth Faltering in Bangladeshi Infants. Am J Epidemiol. 2018 Oct 1;187(10):2210-2218. Cited 41 times.
• Korpe PS, Gilchrist C, Burkey C, Taniuchi M, Ahmed E, Madan V, Castillo R, Ahmed S, Arju T, Alam M, Kabir M, Ahmed T, Petri WA Jr, Haque R, Faruque ASG, Duggal P. Case-Control Study of Cryptosporidium Transmission in Bangladeshi Households. Clin Infect Dis. 2018 Sep 6. Cited 20 times.
• Schnee AE, Haque R, Taniuchi M, Uddin MJ, Petri WA Jr. Evaluation of Two New Membrane-Based and Microtiter Plate Enzyme-Linked Immunosorbent Assays for Detection of Campylobacter jejuni in Stools of Bangladeshi Children. J Clin Microbiol. 2018 Aug 27;56(9). Cited 6 times.
• Kabir M, Ahmed E, Hossain B, Alam M, Ahmed S, Taniuchi M, Gilchrist CA, Houpt ER, Faruque ASG, Petri WA Jr, Haque R. Giardia/Cryptosporidium QUIK CHEK® Assay is more Specific than qPCR for Rapid Point-of-care Diagnosis of Cryptosporidiosis in Infants in Bangladesh. Clin Infect Dis. 2018 Apr 27. Cited 13 times.
• Lee B, Dickson DM, deCamp AC, Colgate ER, Diehl SA, Uddin MI, Sharmin S, Islam S, Bhuiyan TR, Alam M, Nayak U, Mychaleckyj JC, Taniuchi M, Petri WA Jr., Haque R, Qadri F, Kirkpatrick BD. Histoblood Group Antigen Phenotype Determines Susceptibility to Genotype-specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy. J Infect Dis. 2018 Jan 30. Cited 61 times.

2017

• Taniuchi M*, Famulare M, Zaman K, Uddin MJ, Upfill-Brown AM, Ahmed T, Saha P, Haque R, Bandyopadhyay AS, Modlin JF, Platts-Mills JA, Houpt ER, Yunus M, Petri WA Jr. Community transmission of type 2 poliovirus after cessation of trivalent oral polio vaccine in Bangladesh: an open-label cluster-randomised trial and modelling study. Lancet Infect Dis. 2017 Oct;17(10):1069-1079 Jul 7. Cited 21 times.
• Platts-Mills JA, Taniuchi M, Uddin MJ, Sobuz SU, Mahfuz M, Gaffar SA, Mondal D, Hossain MI, Islam MM, Ahmed AS, Petri WA, Haque R, Houpt ER, Ahmed T. Association between enteropathogens and malnutrition in children aged 6-23 mo in Bangladesh: a case-control study. Am J Clin Nutr. 2017 Apr 5. Cited 56 times.
• Upfill-Brown A, Taniuchi M, Platts-Mills JA, Kirkpatrick B, Burgess SL, Oberste MS, Weldon W, Houpt E, Haque R, Zaman K, Petri WA Jr. Non-Specific Effects of Oral Polio Vaccine on Diarrheal Burden and Etiology among Bangladeshi Infants. Clin Infect Dis. 2017 Apr 24. Cited 45 times.
• Giri S, Rajan AK, Kumar N, Dhanapal P, Venkatesan J, Iturriza-Gomara M, Taniuchi M, John J, Abraham AM, Kang G. Comparison of culture, single and multiplex real-time PCR for detection of Sabin poliovirus shedding in recently vaccinated Indian children. J Med Virol. 2017 Feb 18. Cited 5 times.

2016

• Liu J, Platts-Mills JA, Juma J, Kabir F, Nkeze J, Okoi C, Operario DJ, Uddin J, Ahmed S, Alonso PL, Antonio M, Becker SM, Blackwelder WC, Breiman RF, Faruque AS, Fields B, Gratz J, Haque R, Hossain A, Hossain MJ, Jarju S, Qamar F, Iqbal NT, Kwambana B, Mandomando I, McMurry TL, Ochieng C, Ochieng JB, Ochieng M, Onyango C, Panchalingam S, Kalam A, Aziz F, Qureshi S, Ramamurthy T, Roberts JH, Saha D, Sow SO, Stroup SE, Sur D, Tamboura B, Taniuchi M, Tennant SM, Toema D, Wu Y, Zaidi A, Nataro JP, Kotloff KL, Levine MM, Houpt ER. Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study. Lancet. 2016 Sep 24;388(10051):1291-301. Cited 533 times.
• Taniuchi M*, Platts–Mills JA, Begum S, Uddin MJ, Sobuz SU, Liu J, Kirkpatrick BD, Colgate R, Carmolli MP, Dickson DM, Nayak U, Haque R, Petri WA, Houpt ER. Impact of Enterovirus and Other Enteric Pathogens on Oral Polio and Rotavirus Vaccine Performance in Bangladeshi Infants Vaccine. 2016 Jun 8;34(27):3068-75. Cited 81 times.
• Mychaleckyj JC, Haque R, Carmolli M, Zhang D, Colgate ER, Nayak U, Taniuchi M, Dickson D, Weldon WC, Oberste MS, Zaman K, Houpt ER, Alam M, Kirkpatrick BD, Petri WA Jr. Effect of substituting IPV for tOPV on immunity to poliovirus in Bangladeshi infants: An open-label randomized controlled trial. Vaccine. 2016 Jan 12;34(3):358-66. Cited 8 times.

2015

• Kirkpatrick BD, Colgate ER, Mychaleckyj JC, Haque R, Dickson DM, Carmolli MP, Nayak U, Taniuchi M, Naylor C, Qadri F, Ma JZ, Alam M, Walsh MC, Diehl SA; PROVIDE Study Teams, Petri WA Jr. The “Performance of Rotavirus and Oral Polio Vaccines in Developing Countries” (PROVIDE) Study: Description of Methods of an Interventional Study Designed to Explore Complex Biologic Problems. Am J Trop Med Hyg. 2015 Apr 1;92(4):744-51. Cited 82 times.
• Taniuchi M*, Begum S, Uddin MJ, Platts-Mills JA, Liu J, Kirkpatrick BD, Chowdhuryd AH, Jamil KM, Haque R, Petri WA, Jr, Houpt ER. Kinetics of polio shedding following oral vaccination as measured by qRT-PCR versus culture. J Clin Microbiol 2015 Jan;53(1):206-11. Cited 15 times.

2014

• Houpt E, Gratz J, Kosek M, Zaidi AK, Qureshi S, Kang G, Babji S, Mason C, Bodhidatta L, Samie A, Bessong P, Barrett L, Lima A, Havt A, Haque R, Mondal D, Taniuchi M, Stroup S, McGrath M, Lang D; MAL-ED Network Investigators. Microbiologic Methods Utilized in the MAL-ED Cohort Study. Clin Infect Dis. 2014 Nov 1;59 Suppl 4:S225-32. Cited 79 times.
• Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, Gratz J, Becker SM, Operario DJ, Taniuchi M, Janaki L, Platts-Mills JA, Haverstick DM, Kabir M, Sobuz SU, Nakjarung K, Sakpaisal P, Silapong S, Bodhidatta L, Qureshi S, Kalam A, Saidi Q, Swai N, Mujaga B, Maro A, Kwambana B, Dione M, Antonio M, Kibiki G, Mason CJ, Haque R, Iqbal N, Zaidi AK, Houpt ER. Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study. Lancet Infect Dis. 2014 Aug;14(8):716-24. Cited 224 times.
• Jiang NM, Tofail F, Moonah SN, Scharf RJ, Taniuchi M, Ma JZ, Hamadani JD, Gurley ES, Houpt ER, Azziz-Baumgartner E, Haque R, Petri WA Jr. Febrile illness and pro-inflammatory cytokines are associated with lower neurodevelopmental scores in Bangladeshi infants living in poverty. BMC Pediatr. 2014 Feb 18;14:50. Cited 63 times.
• Platts-Mills JA, Liu J, Gratz J, Mduma E, Amour C, Swai N, Taniuchi M, Begum S, Peñataro Yori P, Tilley DH, Lee G, Shen Z, Whary MT, Fox JG, McGrath M, Kosek M, Haque R, Houpt ER. Detection of Campylobacter in stool and determination of significance by culture, enzyme immunoassay, and PCR in developing countries. J Clin Microbiol. 2014 Apr;52(4):1074-80. Cited 67 times.

2013

• Taniuchi M, Sobuz SU, Begum S, Platts-Mills J, Liu J, Yang Z, Wang X, Petri WA Jr, Haque R, Houpt ER*. Etiology of Diarrhea in Bangladeshi Infants in the First Year of Life Using Molecular Methods. J Infect Dis. 2013 Dec 1;208(11):1794-802 Cited 150 times.
• Liu J, Gratz J, Amour C, Kibiki G, Becker S, Janaki L, Verweij JJ, Taniuchi M, Sobuz SU, Haque R, Haverstick DM, Houpt ER. A laboratory-developed TaqMan Array Card for simultaneous detection of 19 pathogens. J Clin Microbiol. 2013 Feb;51(2):472-80. Cited 269 times.

2012

• Nelson AM, Walk ST, Taube S, Taniuchi M, Houpt ER, Wobus CE, Young VB. Disruption of the human gut microbiota following Norovirus infection. PLoS One. 2012;7(10):e48224. Cited 93 times.
• Shimokawa C, Kabir M, Taniuchi M, Mondal D, Kobayashi S, Ali IK, Sobuz SU, Senba M, Houpt E, Haque R, Petri WA Jr, Hamano S. Entamoeba moshkovskii is associated with diarrhea in infants and causes diarrhea and colitis in mice. J Infect Dis. 2012 Sep 1;206(5):744-51. Cited 48 times.
• Taniuchi M*, Walters CC, Gratz J, Maro A, Kumburu H, Serichantalergs O, Sethabutr O, Bodhidatta L, Kibiki G, Toney DM, Berkeley L, Nataro JP, Houpt ER. Development of a multiplex polymerase chain reaction assay for diarrheagenic Escherichia coli and Shigella spp. and its evaluation on colonies, culture broths, and stool. Diagn Microbiol Infect Dis. 2012 Jun;73(2):121-8. Cited 39 times.

2011

• Liu J, Gratz J, Maro A, Kumburu H, Kibiki G, Taniuchi M, Howlader AM, Sobuz SU, Haque R, Talukder KA, Qureshi S, Zaidi A, Haverstick DM, Houpt ER. Simultaneous detection of six diarrhea-causing bacterial pathogens with an in-house PCR-luminex assay. J Clin Microbiol. 2012 Jan;50(1):98-103. Cited 63 times.
• Taniuchi M*, Verweij JJ, Sethabutr O, Bodhidatta L, Garcia L, Maro A, Kumburu H, Gratz J, Kibiki G, Houpt ER.  Multiplex polymerase chain reaction method to detect Cyclospora, Cystoisospora, and Microsporidia in stool samples. Diagn Microbiol Infect Dis. 2011 Dec;71(4):386-90. Cited 48 times.
• Taniuchi M*, Verweij JJ, Noor Z, Sobuz SU, Lieshout Lv, Petri WA Jr, Haque R, Houpt ER. High throughput multiplex PCR and probe-based detection with Luminex beads for seven intestinal parasites. Am J Trop Med Hyg. 2011 Feb;84(2):332-7. Cited 151 times.
• Liu J, Kibiki G, Maro V, Maro A, Kumburu H, Swai N, Taniuchi M, Gratz J, Toney D, Kang G, Houpt E. Multiplex reverse transcription PCR Luminex assay for detection and quantitation of viral agents of gastroenteritis. J Clin Virol. 2011 Apr;50(4):308-13. Cited 93 times.

Position: Research Technician
Email: ewf3a@virginia.edu

Emily Freeman received her undergraduate degree in Theatrical Production Arts from Ithaca College. She is looking toward moving away from what she initially got her degree in and looking forward to exploring the science world while bringing some of her prior experience in a completely different field. She is an avid reader in her free time and loves eating good food with friends and family.

Position: Graduate Student
Email: vaa3qb@virginia.edu

Position: Graduate Student

Md Ohedul Islam (Kajol) is a PhD student at the University of Virginia’s Department of Civil and Environmental Engineering. With over seven years of experience in infectious diseases and wastewater surveillance in low- and middle-income countries, he brings expertise in both laboratory and field. Having led teams in one of the largest real-time sewage surveillance projects for SARS-CoV-2 during the COVID-19 pandemic in Bangladesh, he is deeply passionate about advancing wastewater surveillance and infectious disease epidemiology modeling. Currently, he is focusing on developing the sampling component of wastewater surveillance for enteric pathogens, especially enterovirus and poliovirus, within the Taniuchi Lab. With a passion for bridging the gap between public health and environmental engineering, he is committed to driving forward the understanding of disease transmission dynamics in the environment and informing evidence-based interventions for global health.

Position: Graduate Student

Tahmina Ahmed is a Ph.D. candidate in the Department of Civil and Environmental Engineering at the University of Virginia. Her research focuses on developing a sensitive molecular method to quantitatively differentiate between live and dead microorganisms in environmental samples. Additionally, her interests extend to investigating novel water treatment interventions in low—and middle-income countries. Tahmina earned her Bachelor’s and Master’s degrees from the University of Dhaka, Bangladesh. Beyond the laboratory, you might find her playing the ukulele, cooking, and hiking.

Position: Research Scientist

Dr. Suporn Pholwat grew up in a small village in northeastern Thailand. She left rural Thailand for a better education and received a PhD in Medical and Molecular Microbiology from Mahidol University in Thailand. After receiving the 2009 Pfizer Initiative in International Health Research Fellowship through the Center for Global Health Equity at the University of Virginia, she moved to Charlottesville, VA to pursue a research career in infectious diseases. She worked as a laboratory specialist in the Division of Infectious Diseases and International Health at the University of Virginia under Dr.Eric Houpt’s supervision since 2011, where her primary research focus is molecular diagnostics for tuberculosis, pneumococci, malaria, and antimicrobial-resistant bacteria (AMR). She joined Dr. Mami Taniuchi’s lab as a research scientist in 2021, where she continued her expertise in molecular diagnostics while focusing on wastewater surveillance. In addition, she spends significant time educating the next generation of scientists and working closely with other researchers, especially in low to middle-income countries, to build capacity in molecular diagnostics and next-generation sequencing.

Position: Laboratory Specialist

Erin Wettstone received her undergraduate degree in Biomedical Engineering from the University of Virginia. Her interests surround engineering applications to health disparities and infectious disease research in low-income settings. She is designing and developing a dashboard tool that simultaneously displays environmental surveillance of infectious pathogens and clinical case data in Dhaka, Bangladesh. Read HERE.

Erin handles tasks for our team, such as IRB applications, procurement, and shipping to international research sites. She also helps with fieldwork in Pakistan, Bangladesh, and Tanzania, assists with developing laboratory methods, and writes R analyses. You can find her hiking or exploring new places in Charlottesville in her free time.