Virology and HIV
Virology research at UVA utilizes a number of approaches, including immunology, cell biology, structural biology and cancer biology, to study viruses that include influenza, hepatitis C, Ebola, dengue, KSHV and HIV.
Much of the basic research in HIV is conducted at the Myles H. Thaler Center for AIDS and Human Retrovirus Research, a community of infectious disease and immunology experts that ranks among the best in the nation. Researchers address fundamental questions about how HIV replicates at the cellular and molecular level, and how AIDS develops.
Understanding how exposures in the intestine can influence the broader immune system.
Multi-level intervention design and evaluation to support better integrated care and improved outcomes for people living with HIV, Hepatitis C and substance use disorder.
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika
Immune regulation for HCV infection and chronic liver inflammation
Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.
Human Herpes virus associated with malignancy, including Kaposi's Sarcoma
Pathogenicity of Francisella tularensis and vaccines
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation