Global Biothreats and Emerging Infectious Diseases
Emerging infectious diseases can be defined as infectious diseases that have newly appeared in a population or have previously existed but are rapidly increasing in incidence or geographic range. Biodefense pathogens are those that pose a risk to national security and/or public health, as defined by the National Institute of Allergy and Infectious Diseases’ (NIAID’s) list of category A, B, or C priority pathogens.
Research related to these urgent health threats encompasses a broad spectrum of themes, including investigations of pathogenicity and host responses, vaccines, therapeutics and diagnostic technologies.
The following interdisciplinary faculty conduct research and instruct fellows in this area:
Genetic approaches, cellular and molecular biology of intracellular pathogen infection
Criss, Alison K.
Cellular and molecular mechanisms of Neisserial pathogenesis
Engel, Daniel A.
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika
Hewlett, Erik L.
Structure and Function of Bacterial Toxins: Roles in Microbial Pathogenesis and Uses in Biomedical Research
Houpt, Eric Robert
Molecular diagnostics, Tuberculosis, Global Health
Hughes, Molly A.
Biodefense and emerging pathogens
Kasson, Peter M.
Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.
Kendall, Melissa M.
Bacterial cell signaling, host-pathogen interactions, intestinal pathogens
Kosek, Margaret N.
Mann, Barbara J.
SARS CoV-2 Vaccines and Therapeutics; Pathogenicity of Francisella tularensis and vaccines
Human intestinal parasitology
Moonah, Shannon N.
Host-pathogen interactions; molecular parasitology; mucosal inflammation; immunopathology and repair. Our research interests evolved from studying a parasite that causes inflammation of the gut, similar to IBD.
Petri, William A.
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Platts-Mills, James A
Enteric diseases, molecular diagnostics and infectious disease epidemiology.
Tamm, Lukas K.
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions
Molecular diagnostics; Polio eradication; tracking immunity and virus shedding after oral polio vaccination in resource-challenged countries.