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Global Biothreats and Emerging Infectious Diseases

Emerging infectious diseases can be defined as infectious diseases that have newly appeared in a population or have previously existed but are rapidly increasing in incidence or geographic range. Biodefense pathogens are those that pose a risk to national security and/or public health, as defined by the National Institute of Allergy and Infectious Diseases’ (NIAID’s) list of category A, B, or C priority pathogens.

Research related to these urgent health threats encompasses a broad spectrum of themes, including investigations of pathogenicity and host responses, vaccines, therapeutics and diagnostic technologies.

The following interdisciplinary faculty conduct research and instruct fellows in this area:

Herve Agaisse

Agaisse, Hervé

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Alison Criss

Criss, Alison K.

Cellular and molecular mechanisms of Neisserial pathogenesis

Daniel Engel

Engel, Daniel A.

Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika

Eric Houpt

Houpt, Eric Robert

Molecular diagnostics, Tuberculosis, Global Health

Molly Hughes

Hughes, Molly A.

Biodefense and emerging pathogens

Melissa Kendall

Kendall, Melissa M.

Bacterial cell signaling, host-pathogen interactions, intestinal pathogens

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Kosek, Margaret N.

Infectious Diseases

Chelsea Marie

Marie, Chelsea

Human intestinal parasitology

Shannon Moonah

Moonah, Shannon N.

Host-pathogen interactions; molecular parasitology; mucosal inflammation; immunopathology and repair. Our research interests evolved from studying a parasite that causes inflammation of the gut, similar to IBD.

William Petri

Petri, William A.

Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections

James Platts-Mills

Platts-Mills, James A

Enteric diseases, molecular diagnostics and infectious disease epidemiology.

Girija Ramakrishnan

Ramakrishnan, Girija

Microbial Pathogenesis

Lukas Tamm

Tamm, Lukas K.

Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Mami Taniuchi

Taniuchi, Mami

Molecular diagnostics; Polio eradication; tracking immunity and virus shedding after oral polio vaccination in resource-challenged countries.