Pathogenesis and Host Responses to Infectious Agents
Microbial pathogens, host responses to infection, and pathogen manipulation of host cell biology are the focus of investigation for UVA faculty from a range of disciplines. Many are members of the Carter Immunology Center and the Myles H. Thaler Center for AIDS and Human Retrovirus Research.
The following interdisciplinary faculty conduct research and instruct fellows in this area:
Agaisse, Hervé
Genetic approaches, cellular and molecular biology of intracellular pathogen infection
Burgess, Stacey L.
Understanding how exposures in the intestine can influence the broader immune system.
Casanova, James E.
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.
Moonah, Shannon N.
Host-pathogen interactions; molecular parasitology; mucosal inflammation; immunopathology and repair. Our research interests evolved from studying a parasite that causes inflammation of the gut, similar to IBD.
Shin, Jae Hyun
Clostridium difficile infection, infection in aged host, microbiome-immune response interactions, innate immune response
Sifri, Costi D.
Hospital epidemiology, immunocompromised infectious diseases, molecular pathogenesis and epidemiology, innate immunity
Warren, Cirle A.
Prevention and treatment of C. difficile infection. Role of microbiota in health and disease. Infections in special populations- elderly, pregnant women and racial/ethnic minority groups.