Parasitology / International Health
International health research has long been a focus and strength of the division. Faculty not only work on pathogens of global concern, they do so in collaboration with overseas investigators and at partner study sites in Brazil, Bangladesh, Tanzania, Uganda and elsewhere. Many of these sites represent long-standing partnerships cultivated over years of grant-supported study.
Areas of investigation include diarrheal pathogens, malaria, diagnostics for Mycobacterium tuberculosis, the impact of childhood malnutrition, and the genetics of disease susceptibility.
The following interdisciplinary faculty conduct research and instruct fellows in this area:
Amebiasis vaccine development; biomarkers of Clostridium difficile disease severity
Identification of Parasite Virulence Factors
Enteric infections, toxin mechanisms, pathogenesis and long-term impact
Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum
Multidrug resistant tuberculosis (MDR-TB); pharmacokinetics; clinical application of diagnostics for TB; clinical trials to optimize TB treatment; chronic illness/ TB integration
Molecular diagnostics, Tuberculosis, Global Health
Human intestinal parasitology
Host-pathogen interactions; molecular parasitology; mucosal inflammation; immunopathology and repair. Our research interests evolved from studying a parasite that causes inflammation of the gut, similar to IBD.
Sepsis pathophysiology with particular interest in the role of the innate immune system; sepsis pathophysiology, management, and outcomes of HIV infected patients in sub-Saharan Africa.
Enteric diseases, molecular diagnostics and infectious disease epidemiology.
Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections
Molecular diagnostics; Polio eradication; tracking immunity and virus shedding after oral polio vaccination in resource-challenged countries.
Pediatric tuberculosis: epidemiology and biomarkers for diagnosis/prognosis