Whether they are working to perceive sound, defend us from pathogens or digest and absorb nutrients, our cells are constantly exposed to changing forces in their physical environment. The Ebrahim Lab focuses on how cells perceive and respond to these changes- their mechanobiology – during tissue function and dysfunction. We are especially interested in the roles and regulation of dynamic cytoskeletal networks and mechanosensitive ion channels in intestinal epithelia during inflammation, cancer and aging.

The lab uses a combination of innovative, super-resolution live cell and in vivo tissue imaging, quantitative cell biology approaches and mouse models to gain new insights into the mechanobiology of epithelial homeostasis and disease.

We currently have positions available for talented scientists at undergraduate, graduate and post-doctoral levels. If you are interested, please contact Dr. Ebrahim: seham.ebrahim@virginia.edu.