6/17/2025
Tyrosine phosphorylation is a protein modification that can occur during or after translation of a protein.The phosphate addition to a tyrosine residue, regulated by tyrosine kinases and phosphatases, can result…
6/17/2025
Innate immunity provides the first line of defense against pathogens, which is critically important to limit their replication and spread. However, overactivation of innate immunity causes autoimmune diseases and may…
6/17/2025
The primary goal of our lab is to understand the neural code underlying the generation of different motivated behaviors (e.g. feeding, drinking, and social interaction), with a focus on how…
6/17/2025
All the way up to the 20th century, the human genome has been optimized to survive in environments characterized by fluctuations between periods of feast and famine. These survivor-genomes clash…
6/17/2025
The Pani lab pursues curiosity-driven research exploring the cell biological foundations of development and tissue maintenance. Cell-cell signaling performs critical functions in development, homeostasis, and disease. In normal conditions, cell signaling…
6/17/2025
Much of our work focuses on cell signaling and mechanisms of lineage specification, differentiation and morphogenesis. Particular emphases have been on post-embryonic neural crest stem cells and their derivatives, including…
6/17/2025
Director of Graduate Studies for Microbiology, Immunology and Cancer BiologyPlease contact Dr. Pemberton for any information or guidance regarding our graduate program. Associate Director of Education, UVA Comprehensive Cancer CenterDr…
6/17/2025
My laboratory aims to explore the physiological role of endoplasmic reticulum (ER) homeostasis (with a special focus on ER-associated degradation, ERAD) in the context of human diseases. We use genetic,…
6/17/2025
All eukaryotic cells divide by assembling a microtubule-based spindle machinery that equally segregates chromosomes between daughter cells. The faithful segregation of chromosomes during cell division is essential as errors in…
6/17/2025
Our team studies how neurons assemble into circuits and how those circuits adapt to the environment. We use state-of-the-art neuroscience tools in the rodent visual system to ultimately understand how learning…
