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Georgio Mantziaris, MD

Prior Training & Education

Clinical Fellow, Neuro-oncology CAST Fellowship, Department of Neurosurgery, University of Virginia, 2023-25

Postdoctoral research fellow, Department of Neurosurgery, University of Virginia, 2021-23

Resident in Neurosurgery, Hellenic Red Cross Hospital, Athens, Greece, 2014-2020

MD, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, 2014

Email: URF4WF@uvahealth.org

Publications

Stereotactic Radiosurgery Versus Observation in Small- and Medium-Sized Vestibular Schwannoma Patients With Normal Hearing: A Retrospective International Multicenter Study

Neurosurgery. 2025 Sep 16. doi: 10.1227/neu.0000000000003734. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: The therapeutic approach for small- and medium-sized vestibular schwannoma (VS) with normal hearing function remains controversial, with limited…

Safety and efficacy of preoperative embolization in the treatment of brain arteriovenous malformations with perinidal aneurysms and single draining vein: a multicenter study with propensity score-weighting

J Neurointerv Surg. 2025 Aug 22:jnis-2025-023873. doi: 10.1136/jnis-2025-023873. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Arteriovenous malformations (AVMs) with perinidal aneurysms and single draining vein are associated with an elevated risk…

Outcome Evaluation of Volume-Staged Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations

Neurosurgery. 2025 Aug 11. doi: 10.1227/neu.0000000000003682. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Single-session stereotactic radiosurgery (SRS) has limited role for large arteriovenous malformations (AVM). Volume-staged SRS (VS-SRS) is used to…

Stereotactic radiosurgery and fractionated radiation therapy in the management of pituitary tumors

Neurooncol Adv. 2024 Dec 19;7(Suppl 1):i58-i68. doi: 10.1093/noajnl/vdae010. eCollection 2025 Jul.ABSTRACTPituitary tumors require a diverse, multidisciplinary approach in their management. Stereotactic radiosurgery (single or hypofractionated) and fractionated radiotherapy are integral…

Radiation-induced cerebral cavernous malformation following stereotactic radiosurgery for a brain metastasis

BMJ Case Rep. 2025 Jul 13;18(7):e265344. doi: 10.1136/bcr-2025-265344.ABSTRACTRadiation-induced cerebral cavernous malformations (RICMs) are rare complications of stereotactic radiosurgery (SRS). We present a woman in her 70s who underwent Gamma Knife…

Impact of smoking on occlusion rates following stereotactic radiosurgery for Spetzler Martin grade I-III brain arteriovenous malformations - A propensity score matched analysis of the MISTA consortium

J Clin Neurosci. 2025 Sep;139:111411. doi: 10.1016/j.jocn.2025.111411. Epub 2025 Jun 27.ABSTRACTBACKGROUNDAND OBJECTIVE: The authors compareocclusion rates in grade I-III AVMs in smokers and non-smokers, using propensity score matching (PSM).METHODS: The…

Outcomes After Stereotactic Radiosurgery for Intracranial Hemangioblastoma in Von Hippel-Lindau Disease and Sporadic Cases: An International Multicenter Study

Neurosurgery. 2025 Jun 19. doi: 10.1227/neu.0000000000003579. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Hemangioblastomas (HGBs) are rare, benign, World Health Organization grade 1 vascular tumors, which are most commonly located in…

Stereotactic radiosurgery for brain metastases

Adv Cancer Res. 2025;165:115-143. doi: 10.1016/bs.acr.2025.04.001. Epub 2025 Apr 24.ABSTRACTBrain metastases are the most common intracranial malignancies in adults, and, depending on primary tumor type, they may affect up to…

Outcomes of stereotactic radiosurgery for pituitary metastases: an international multi-institutional study

Pituitary. 2025 May 29;28(3):69. doi: 10.1007/s11102-025-01542-z.ABSTRACTBACKGROUND: Pituitary metastases (PM) account for 0.4% of all intracranial metastases and typically present with visual and endocrinological deficits. Stereotactic radiosurgery (SRS) has shown excellent…

Revisiting radioresistance: a systematic review of outcomes of Stereotactic radiosurgery (SRS) in functional head and neck paragangliomas

Neurosurg Rev. 2025 May 28;48(1):452. doi: 10.1007/s10143-025-03604-z.ABSTRACTThis systematic review evaluates the role of stereotactic radiosurgery (SRS) in managing functional head and neck paragangliomas (FPG), which pose unique challenges due to…

Outcomes of arteriovenous malformations with single versus multiple draining veins: A multicenter study

J Neurol Sci. 2025 Jun 15;473:123503. doi: 10.1016/j.jns.2025.123503. Epub 2025 Apr 12.ABSTRACTBACKGROUND: Cerebral arteriovenous malformations (AVMs) are complex vascular lesions that pose a risk for hemorrhagic stroke. The number of…

Spetzler-martin grade IV cerebral arteriovenous malformations in adult patients: a propensity-score matched analysis of resection and stereotactic radiosurgery

Neurosurg Rev. 2025 Mar 31;48(1):337. doi: 10.1007/s10143-025-03465-6.ABSTRACTSpetzler-Martin Grade IV arteriovenous malformations (AVMs) are challenging due to high risks associated with both treatment and natural progression. This study compares the outcomes…

Leukoencephalopathy following stereotactic radiosurgery for breast cancer brain metastases: a single-center analysis of 1,077 lesions

Acta Neurochir (Wien). 2025 Mar 14;167(1):73. doi: 10.1007/s00701-025-06478-8.ABSTRACTBACKGROUND: Leukoencephalopathy is the most prevalent and delayed adverse radiation effect (ARE) after intracranial radiotherapy (RT). Patients with leukoencephalopathy experience some levels of…

Spetzler-Martin grade I and II cerebral arteriovenous malformations: a propensity-score matched analysis of resection and stereotactic radiosurgery in adult patients

Neurosurg Rev. 2025 Feb 28;48(1):276. doi: 10.1007/s10143-025-03431-2.ABSTRACTCerebral arteriovenous malformations (AVMs) are congenital vascular anomalies that can lead to severe complications, including hemorrhage and neurological deficits. This study compares the outcomes…

Dosimetric predictors of toxicity for brainstem metastases and AVMs treated with stereotactic radiosurgery: An international, multi-institutional analysis

Radiother Oncol. 2025 May;206:110795. doi: 10.1016/j.radonc.2025.110795. Epub 2025 Feb 19.ABSTRACTBACKGROUND: There are limited data on dosimetric predictors of radiation-induced changes (RICs) for brainstem metastases or arteriovenous malformations (AVMs) following single-fraction…

Comparative outcomes of arteriovenous malformations treatment in eloquent versus non-eloquent brain: A multicenter study with propensity-score weighting

Int J Stroke. 2025 Aug;20(7):852-863. doi: 10.1177/17474930251323503. Epub 2025 Feb 13.ABSTRACTBACKGROUND: Arteriovenous malformations (AVMs) are complex vascular anomalies with a high risk of hemorrhage and neurological deficits, especially when located…

A retrospective comparison of active surveillance to stereotactic radiosurgery for the management of elderly patients with an incidental meningioma

Acta Neurochir (Wien). 2025 Feb 6;167(1):37. doi: 10.1007/s00701-025-06452-4.ABSTRACTINTRODUCTION: Management for elderly patients (> 65yo) with incidental meningiomas remains unclear. This study aims to characterize the functional and tumor outcomes of…

Stereotactic Radiosurgery for World Health Organization Grade 2 and 3 Oligodendroglioma: An International Multicenter Study

Neurosurgery. 2025 Apr 1;96(4):870-880. doi: 10.1227/neu.0000000000003177. Epub 2024 Sep 20.ABSTRACTBACKGROUND AND OBJECTIVES: Oligodendrogliomas are primary brain tumors classified as isocitrate deshydrogenase-mutant and 1p19q codeleted in the 2021 World Health Organization…

The 5-factor modified frailty index as a prognostic factor following stereotactic radiosurgery for metastatic disease to the brain from non-small cell lung cancer: A multi-center cohort analysis

J Clin Neurosci. 2025 Feb;132:110979. doi: 10.1016/j.jocn.2024.110979. Epub 2024 Dec 13.ABSTRACTBACKGROUND: Non-small cell lung cancer (NSCLC) patients often develop brain metastases (BMs), complicating management. We have shown that increasing frailty…

Proton beam and carbon ion radiotherapy in skull base chordoma: a systematic review, meta-analysis and meta-regression with trial sequential analysis

Neurosurg Rev. 2024 Dec 7;47(1):893. doi: 10.1007/s10143-024-03117-1.ABSTRACTChordomas are rare, locally aggressive tumors that have a high rate of recurrence, especially at the skull base. This systematic review and meta-analysis aimed…

Local control and patient survival after stereotactic radiosurgery for esophageal cancer brain metastases: an international multicenter analysis

J Neurosurg. 2024 Dec 6;142(5):1357-1365. doi: 10.3171/2024.7.JNS24920. Print 2025 May 1.ABSTRACTOBJECTIVE: This study aimed to evaluate local control (LC) of tumors, patient overall survival (OS), and the safety of stereotactic…

A comparative analysis of microsurgical resection versus stereotactic radiosurgery for Spetzler-Martin grade III arteriovenous malformations: A multicenter propensity score matched study

Clin Neurol Neurosurg. 2025 Feb;249:108669. doi: 10.1016/j.clineuro.2024.108669. Epub 2024 Dec 3.ABSTRACTBACKGROUND: Spetzler-Martin (SM) Grade III brain arteriovenous malformations (BAVMs) represent a transitional risk zone between low- and high-grade BAVMs, characterized…

Stereotactic Radiosurgery for Pediatric Intracranial Arteriovenous Malformations: Precision Beams and Childhood Dreams

World Neurosurg. 2025 Feb;194:123489. doi: 10.1016/j.wneu.2024.11.072. Epub 2024 Dec 3.NO ABSTRACTPMID:39638646 | DOI:10.1016/j.wneu.2024.11.072

Outcomes Associated With Stereotactic Radiosurgery After Multiple Resections of Nonfunctioning Pituitary Macroadenomas: An International, Multicenter Case Series

Neurosurgery. 2024 Nov 7;97(1):182-190. doi: 10.1227/neu.0000000000003262.ABSTRACTBACKGROUND AND OBJECTIVES: Stereotactic radiosurgery (SRS) represents an effective treatment for nonfunctioning pituitary adenomas (NFPAs). However, no data have yet been published regarding results of…

Stereotactic radiosurgery (SRS) for patients with brainstem cerebral cavernous malformations (CCMs): an international, multicentric study

Sci Rep. 2024 Oct 29;14(1):25933. doi: 10.1038/s41598-024-77140-z.ABSTRACTBrainstem cerebral cavernous malformations (CCM) are clinically more aggressive compared to superficial CCMs. Due to their location, resection can be challenging, making stereotactic radiosurgery…

Stereotactic Radiosurgery Dose Reduction for Melanoma Brain Metastases Patients on Immunotherapy or Target Therapy: A Single-Center Experience

Neurosurgery. 2025 Jun 1;96(6):1307-1320. doi: 10.1227/neu.0000000000003239. Epub 2024 Oct 28.ABSTRACTBACKGROUND AND OBJECTIVES: Better local control but higher rates of adverse radiation events (ARE) have been reported when combining American Society…

Comparative analysis of stereotactic radiosurgery outcomes for supratentorial hemangioblastomas in von hippel-lindau disease and sporadic cases: A multi-center international study

J Clin Neurosci. 2024 Nov;129:110879. doi: 10.1016/j.jocn.2024.110879. Epub 2024 Oct 18.ABSTRACTBACKGROUND: Hemangioblastomas (HBs) are rare, benign central nervous system (CNS) neoplasms that rarely occur in the supratentorial. Resection with the…

Stereotactic radiosurgery for arteriovenous malformations in pediatric patients: an updated systematic review and meta-analysis

J Neurosurg Pediatr. 2024 Oct 4;34(6):591-600. doi: 10.3171/2024.7.PEDS24230. Print 2024 Dec 1.ABSTRACTOBJECTIVE: Intracranial arteriovenous malformations are the most common cause of intracranial hemorrhages in pediatric patients. Stereotactic radiosurgery (SRS) has…

Stereotactic Radiosurgery for Intracranial Cavernous Malformations: International Stereotactic Radiosurgery Society, Systematic Review, Meta-Analysis, and Practice Guidelines

World Neurosurg. 2024 Dec;192:e366-e401. doi: 10.1016/j.wneu.2024.09.106. Epub 2024 Oct 18.ABSTRACTOBJECTIVE: The International Stereotactic Radiosurgery Society aims to establish evidence-based guidelines for single-fraction stereotactic radiosurgery (SRS) in treating intracranial cavernous malformations.METHODS:…

Comparison of Repeat Versus Initial Stereotactic Radiosurgery for Intracranial Arteriovenous Malformations: A Retrospective Multicenter Matched Cohort Study

Neurosurgery. 2024 Oct 1;95(4):904-914. doi: 10.1227/neu.0000000000002950. Epub 2024 Apr 16.ABSTRACTBACKGROUND AND OBJECTIVES: Studies comparing neurological and radiographic outcomes of repeat to initial stereotactic radiosurgery (SRS) intracranial arteriovenous malformations are scarce.…

Biological effective dose as a predictor of local tumor control in stereotactic radiosurgery treated parasellar meningioma patients

J Neurooncol. 2024 Nov;170(2):377-385. doi: 10.1007/s11060-024-04804-1. Epub 2024 Aug 27.ABSTRACTINTRODUCTION: The radio-surgical literature increasingly uses biological effective dose (BED) as a replacement for absorbed dose to analyze outcome of stereotactic…

Stereotactic radiosurgery for brain metastases from human epidermal receptor 2 positive breast Cancer: an international, multi-center study

J Neurooncol. 2024 Oct;170(1):199-208. doi: 10.1007/s11060-024-04775-3. Epub 2024 Aug 27.ABSTRACTPURPOSE: To report patient outcomes and local tumor control rates in a cohort of patients with biopsy-proven HER-2 positive breast cancer…

Assessment of High-fidelity Anatomical Models for Performing Pterional Approach: A Practical Clinic in American Association of Neurological Surgeons Meeting 2024

World Neurosurg. 2024 Oct;190:e137-e143. doi: 10.1016/j.wneu.2024.07.072. Epub 2024 Jul 23.ABSTRACTBACKGROUND: Over the last decade, simulation models have been increasingly applied as an adjunct for surgical training in neurosurgery. We aim…

Risk of new tumor, carotid stenosis, and stroke after stereotactic radiosurgery for pituitary tumor: A multicenter study of 2254 patients with imaging follow-up

Neuro Oncol. 2024 Dec 5;26(12):2328-2338. doi: 10.1093/neuonc/noae133.ABSTRACTBACKGROUND: A higher risk of secondary brain tumor, carotid stenosis, and stroke has been reported after conventional sella irradiation for pituitary neuroendocrine tumors (PitNET).…

Repeat Single-Session Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations: A Systematic Review, Meta-Analysis, and International Stereotactic Radiosurgery Society Practice Guidelines

Neurosurgery. 2025 Jan 1;96(1):29-40. doi: 10.1227/neu.0000000000003049. Epub 2024 Jun 24.ABSTRACTBACKGROUND AND OBJECTIVES: Repeat stereotactic radiosurgery (SRS) for residual arteriovenous malformations (AVMs) can be considered as a salvage approach after failure…

Stereotactic radiosurgery for intracranial cavernous malformations of the deep-seated locations: systematic review and meta-analysis

Neurosurg Rev. 2024 Apr 24;47(1):186. doi: 10.1007/s10143-024-02434-9.ABSTRACTOBJECTIVE: To determine the outcomes of stereotactic radiosurgery (SRS) for deep-seated (brainstem, basal ganglia, thalamus, cerebellar peduncle) intracranial cavernous malformations (ICMs).METHODS: A systematic review…

Comparative analysis of the spatial distribution of brain metastases across several primary cancers using machine learning and deep learning models

J Neurooncol. 2024 May;167(3):501-508. doi: 10.1007/s11060-024-04630-5. Epub 2024 Apr 2.ABSTRACTOBJECTIVE: Brain metastases (BM) are associated with poor prognosis and increased mortality rates, making them a significant clinical challenge. Studying BMs…

Long-term radiographic and endocrinological outcomes of stereotactic radiosurgery for recurrent or residual nonfunctioning pituitary adenomas

J Neurosurg. 2024 Mar 22;141(3):773-780. doi: 10.3171/2024.1.JNS232285. Print 2024 Sep 1.ABSTRACTOBJECTIVE: Stereotactic radiosurgery (SRS) is used for the treatment of residual/recurrent nonfunctional pituitary adenoma (NFPA). The aim of this study…

Single-Session Stereotactic Radiosurgery After Failed Repeat Radiosurgery for Cerebral Arteriovenous Malformations

World Neurosurg. 2024 Apr;184:334. doi: 10.1016/j.wneu.2024.01.114. Epub 2024 Jan 24.NO ABSTRACTPMID:38368153 | DOI:10.1016/j.wneu.2024.01.114

Stereotactic radiosurgery and bevacizumab for recurrent glioblastoma

J Neurooncol. 2024 Mar;167(1):231-232. doi: 10.1007/s11060-024-04592-8. Epub 2024 Feb 16.NO ABSTRACTPMID:38363492 | DOI:10.1007/s11060-024-04592-8

The relevance of biologically effective dose for pain relief and sensory dysfunction after Gamma Knife radiosurgery for trigeminal neuralgia: an 871-patient multicenter study

J Neurosurg. 2024 Feb 16;141(2):461-473. doi: 10.3171/2023.12.JNS231569. Print 2024 Aug 1.ABSTRACTOBJECTIVE: Recent studies have suggested that biologically effective dose (BED) is an important correlate of pain relief and sensory dysfunction…

Facial Nerve Schwannoma Treatment with Stereotactic Radiosurgery (SRS) versus Resection followed by SRS: Outcomes and a Management Protocol

J Neurol Surg B Skull Base. 2022 Dec 30;85(1):75-80. doi: 10.1055/a-1990-2861. eCollection 2024 Feb.ABSTRACTBackground Stereotactic radiosurgery (SRS) and resection are treatment options for patients with facial nerve schwannomas without mass…

Repeat stereotactic radiosurgery for persistent cerebral arteriovenous malformations in pediatric patients

J Neurosurg Pediatr. 2024 Jan 26;33(4):307-314. doi: 10.3171/2023.12.PEDS23465. Print 2024 Apr 1.ABSTRACTOBJECTIVE: The purpose of this study was to describe the long-term outcomes and associated risks related to repeat stereotactic…

Stereotactic radiosurgery for brain arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia

Acta Neurochir (Wien). 2024 Jan 17;166(1):21. doi: 10.1007/s00701-024-05923-4.ABSTRACTOBJECTIVE: Brain arteriovenous malformations (AVMs) in patients with hereditary hemorrhagic telangiectasia (HHT) present different characteristics from sporadic AVMs, and they have lower initial…

Pediatric cerebral cavernous malformations and stereotactic radiosurgery: an analysis of 50 cases from a multicentric study

J Neurosurg Pediatr. 2024 Jan 5;33(4):315-322. doi: 10.3171/2023.11.PEDS23402. Print 2024 Apr 1.ABSTRACTOBJECTIVE: Cerebral cavernous malformations (CCMs) are the second most common vascular anomaly affecting the CNS in children. Although stereotactic…

Effect of cerebral arteriovenous malformation location on outcomes of repeat, single-fraction stereotactic radiosurgery: a matched-cohort analysis

J Neurosurg. 2023 Dec 22;140(6):1753-1761. doi: 10.3171/2023.10.JNS231957. Print 2024 Jun 1.ABSTRACTOBJECTIVE: Patients with deep-seated arteriovenous malformations (AVMs) have a higher rate of unfavorable outcome and lower rate of nidus obliteration…

Third Stereotactic Radiosurgery for Residual Arteriovenous Malformations: A Retrospective Multicenter Study

Neurosurgery. 2023 Dec 18. doi: 10.1227/neu.0000000000002805. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: There are no studies evaluating the efficacy and safety of more than 2 stereotactic radiosurgery (SRS) procedures for…

Stereotactic radiosurgery for nonfunctioning pituitary tumor: A multicenter study of new pituitary hormone deficiency

Neuro Oncol. 2024 Apr 5;26(4):715-723. doi: 10.1093/neuonc/noad215.ABSTRACTBACKGROUND: Stereotactic radiosurgery (SRS) is used to treat recurrent or residual nonfunctioning pituitary neuroendocrine tumors (NFPA). The objective of the study was to assess…

Clinical outcomes following stereotactic radiosurgery for cerebral cavernous malformations of the basal ganglia and thalamus

J Neurosurg. 2023 Dec 8;140(6):1762-1768. doi: 10.3171/2023.10.JNS231894. Print 2024 Jun 1.ABSTRACTOBJECTIVE: There are few reports of outcomes following stereotactic radiosurgery (SRS) for the management of cerebral cavernous malformations (CCMs) of…

Incidental meningiomas: a current and increasingly common challenge

J Neurooncol. 2023 Dec;165(3):569-571. doi: 10.1007/s11060-023-04525-x. Epub 2023 Nov 30.NO ABSTRACTPMID:38032427 | DOI:10.1007/s11060-023-04525-x

Silent Corticotroph Staining Pituitary Neuroendocrine Tumors: Prognostic Significance in Radiosurgery

Neurosurgery. 2023 Dec 1;93(6):1407-1414. doi: 10.1227/neu.0000000000002607. Epub 2023 Jul 25.ABSTRACTBACKGROUND AND OBJECTIVES: There is conflicting evidence on the significance of adrenocorticotrophic hormone (ACTH) staining in the prognosis of nonfunctioning pituitary…

Local control and survival after stereotactic radiosurgery for colorectal cancer brain metastases: an international multicenter analysis

J Neurosurg. 2023 Nov 10;140(5):1233-1242. doi: 10.3171/2023.8.JNS231231. Print 2024 May 1.ABSTRACTOBJECTIVE: The goal of this study was to characterize local tumor control (LC), overall survival (OS), and safety of stereotactic…

Selected-Lesion Stereotactic Radiosurgery (SL-SRS) as a Novel Strategy in the Treatment of Patients With Multiple Brain Metastases

Cureus. 2023 Sep 18;15(9):e45457. doi: 10.7759/cureus.45457. eCollection 2023 Sep.ABSTRACTINTRODUCTION: With the diminishing use of whole-brain radiotherapy (WBRT), there is increasing debate regarding the maximum number of brain metastases that should…

Biologically Effective Dose and Prediction of Obliteration of Arteriovenous Malformations in Pediatric Patients Treated by Gamma Knife Radiosurgery

Neurosurgery. 2024 Mar 1;94(3):614-621. doi: 10.1227/neu.0000000000002717. Epub 2023 Oct 13.ABSTRACTBACKGROUND AND OBJECTIVES: Stereotactic radiosurgery (SRS) represents an effective treatment for pediatric arteriovenous malformations (AVMs). Biological effective dose (BED) has shown…

Stereotactic radiosurgery for haemorrhagic cerebral cavernous malformation: a multi-institutional, retrospective study

Stroke Vasc Neurol. 2024 Jun 21;9(3):221-229. doi: 10.1136/svn-2023-002380.ABSTRACTBACKGROUND: Cerebral cavernous malformations (CCMs) frequently manifest with haemorrhages. Stereotactic radiosurgery (SRS) has been employed for CCM not suitable for resection. Its effect…

Intratumoral Hemorrhage in Vestibular Schwannomas After Stereotactic Radiosurgery: Multi-Institutional Study

Neurosurgery. 2024 Feb 1;94(2):289-296. doi: 10.1227/neu.0000000000002627. Epub 2023 Aug 15.ABSTRACTBACKGROUND AND OBJECTIVES: Intratumoral hemorrhage (ITH) in vestibular schwannoma (VS) after stereotactic radiosurgery (SRS) is exceedingly rare. The aim of this…

Incorporation of Brain Connectomics for Stereotactic Radiosurgery Treatment Planning

Oper Neurosurg. 2023 Oct 1;25(4):e211-e215. doi: 10.1227/ons.0000000000000818. Epub 2023 Aug 3.ABSTRACTBACKGROUND AND IMPORTANCE: Neurosurgeons have integrated neuroanatomy-based tractography to avoid critical structures during dose planning. However, they have yet to…

Volumetric Assessment of Nonfunctional Pituitary Adenoma Treated With Stereotactic Radiosurgery: An Assessment of Long-Term Response

Neurosurgery. 2023 Dec 1;93(6):1339-1345. doi: 10.1227/neu.0000000000002594. Epub 2023 Jul 12.ABSTRACTBACKGROUND AND OBJECTIVES: Stereotactic radiosurgery (SRS) is widely used to manage recurrent or residual nonfunctioning pituitary adenomas (NFPAs). Studies on the…

Diffusivity metrics alterations three months after GammaKnife radiosurgery for trigeminal neuralgia may predict pain relief

J Radiosurg SBRT. 2022;8(4):241-246.ABSTRACTOBJECTIVES: Early identification of patients who will experience delayed-onset pain relief after GKRS for trigeminal neuralgia (TN) will allow optimal patient management, and avoidance of unnecessary procedures.…

Epilepsy associated with cerebral cavernous malformations managed with stereotactic radiosurgery: an international, multicenter study

J Neurol. 2023 Oct;270(10):5048-5056. doi: 10.1007/s00415-023-11836-6. Epub 2023 Jul 5.ABSTRACTOBJECTIVE: Stereotactic radiosurgery (SRS) has been proposed as an alternative to resection for epilepsy control in patients with cerebral cavernous malformations…

Outcome Evaluation of Repeat Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations

Stroke. 2023 Aug;54(8):1974-1984. doi: 10.1161/STROKEAHA.123.042515. Epub 2023 Jun 23.ABSTRACTBACKGROUND: Repeat stereotactic radiosurgery (SRS) for persistent cerebral arteriovenous malformation (AVM) has generally favorable patient outcomes. However, reporting studies are limited by…

Chat GPT versus human touch in stereotactic radiosurgery

J Neurooncol. 2023 Jun;163(2):481-483. doi: 10.1007/s11060-023-04353-z. Epub 2023 May 29.NO ABSTRACTPMID:37247179 | DOI:10.1007/s11060-023-04353-z

Stereotactic Radiosurgery for Meningiomas in Children and Adolescents: An International Multi-Institutional Study

Neurosurgery. 2023 Nov 1;93(5):1066-1074. doi: 10.1227/neu.0000000000002543. Epub 2023 May 26.ABSTRACTBACKGROUND AND OBJECTIVES: Meningiomas in children are uncommon, with distinct characteristics that set them apart from their adult counterparts. The existing…

Stereotactic Radiosurgery for Intracranial Meningiomas

Neurosurg Clin N Am. 2023 Jul;34(3):455-462. doi: 10.1016/j.nec.2023.02.010. Epub 2023 Apr 7.ABSTRACTMeningiomas are thought to originate from the meningothelial cells of the arachnoid mater and are the most common primary…

Adjuvant Stereotactic Radiosurgery With or Without Postresection Fractionated Radiation Therapy for the Management of Clival Chordomas in Adults: An International Multicenter Case Series

Neurosurgery. 2023 Oct 1;93(4):892-900. doi: 10.1227/neu.0000000000002488. Epub 2023 Apr 13.ABSTRACTBACKGROUND: Clival chordomas are challenging because of their proximity to critical neurovascular structures. Stereotactic radiosurgery (SRS) has been proven effective with…

Local Control and Survival Outcomes After Stereotactic Radiosurgery for Brain Metastases From Gastrointestinal Primaries: An International Multicenter Analysis

Neurosurgery. 2023 Sep 1;93(3):592-598. doi: 10.1227/neu.0000000000002456. Epub 2023 Mar 21.ABSTRACTBACKGROUND: There are limited data regarding outcomes for patients with gastrointestinal (GI) primaries and brain metastases treated with stereotactic radiosurgery (SRS).OBJECTIVE:…

Stereotactic radiosurgery for Koos grade IV vestibular schwannoma in patients ≥ 65 years old: a multi-institutional retrospective study

Acta Neurochir (Wien). 2023 Jan;165(1):211-220. doi: 10.1007/s00701-022-05454-w. Epub 2022 Dec 22.ABSTRACTBACKGROUND: Surgery is the preferred treatment for large vestibular schwannomas (VS). Good tumor control and cranial nerve outcomes were described…

Stereotactic Radiosurgery for Intraventricular Metastases: A Multicenter Study

Neurosurgery. 2023 Mar 1;92(3):565-573. doi: 10.1227/neu.0000000000002248. Epub 2022 Dec 7.ABSTRACTBACKGROUND: Intraventricular metastases (IVMs) are uncommon, and their optimal management remains debatable.OBJECTIVE: To define the safety and efficacy of stereotactic radiosurgery…

Role of biological effective dose for prediction of endocrine remission in acromegaly patients treated with stereotactic radiosurgery

Pituitary. 2023 Feb;26(1):124-131. doi: 10.1007/s11102-022-01293-1. Epub 2022 Dec 5.ABSTRACTPURPOSE: Stereotactic radiosurgery (SRS) can be used in acromegaly patients to achieve endocrine remission. In this study we evaluate the biological effective…

Adjuvant versus on-progression Gamma Knife radiosurgery for residual nonfunctioning pituitary adenomas: a matched-cohort analysis

J Neurosurg. 2022 Nov 18;138(6):1662-1668. doi: 10.3171/2022.10.JNS221873. Print 2023 Jun 1.ABSTRACTOBJECTIVE: Radiological progression occurs in 50%-60% of residual nonfunctioning pituitary adenomas (NFPAs). Stereotactic radiosurgery (SRS) is a safe and effective…

Stereotactic radiosurgery for Koos grade IV vestibular schwannoma: a multi-institutional study

J Neurosurg. 2022 Jun 3;138(2):405-412. doi: 10.3171/2022.4.JNS22203. Print 2023 Feb 1.ABSTRACTOBJECTIVE: Though stereotactic radiosurgery (SRS) is an established safe treatment for small- and medium-sized vestibular schwannomas (VSs), its role in…

Stereotactic radiosurgery for sellar solitary fibrous tumors: Case report and literature review

J Radiosurg SBRT. 2022;8(2):159-163.NO ABSTRACTPMID:36275131 | PMC:PMC9489078

Stereotactic radiosurgery for Koos grade IV vestibular schwannoma in young patients: a multi-institutional study

J Neurooncol. 2022 Oct;160(1):201-208. doi: 10.1007/s11060-022-04134-0. Epub 2022 Sep 27.ABSTRACTPURPOSE: Surgery is the treatment of choice for large vestibular schwannomas (VS). Stereotactic radiosurgery (SRS) has been suggested as an alternative…

Spontaneous Spinal Epidural Hematoma in a Patient on Rivaroxaban: A Case Report

Neurol India. 2022 Jul-Aug;70(4):1674-1675. doi: 10.4103/0028-3886.355150.NO ABSTRACTPMID:36076684 | DOI:10.4103/0028-3886.355150

Repeat stereotactic radiosurgery for cerebral arteriovenous malformations

Neurosurg Focus. 2022 Jul;53(1):E11. doi: 10.3171/2022.4.FOCUS2294.ABSTRACTOBJECTIVE: The purpose of this retrospective, single-institution study was to evaluate radiological and clinical outcomes of patients managed with repeat stereotactic radiosurgery (SRS) for residual…

Stereotactic Radiosurgery for Intracranial Primary Melanocytomas

World Neurosurg. 2022 Aug;164:160-166. doi: 10.1016/j.wneu.2022.04.136. Epub 2022 May 10.ABSTRACTOBJECTIVE: The role of stereotactic radiosurgery (SRS) in the management of recurrent and residual intracranial primary melanocytomas (PMC) remains unclear. The…

Stereotactic radiosurgery for the treatment of hypoglossal schwannoma: a multi-institutional retrospective study

Acta Neurochir (Wien). 2022 Sep;164(9):2473-2481. doi: 10.1007/s00701-022-05187-w. Epub 2022 Mar 26.ABSTRACTBACKGROUND: Surgical removal has been performed as the first line treatment for symptomatic or enlarging hypoglossal schwannomas (HS). Stereotactic radiosurgery…

Radiological and clinical outcomes of stereotactic radiosurgery for gangliogliomas: an international multicenter study

J Neurosurg. 2022 Mar 25;137(5):1248-1253. doi: 10.3171/2022.2.JNS212813. Print 2022 Nov 1.ABSTRACTOBJECTIVE: The optimal treatment for recurrent and residual gangliogliomas remains unclear. The aim of this study was to evaluate the…

Stereotactic Radiosurgery Compared With Active Surveillance for Asymptomatic, Parafalcine, and Parasagittal Meningiomas: A Matched Cohort Analysis From the IMPASSE Study

Neurosurgery. 2022 Jun 1;90(6):750-757. doi: 10.1227/neu.0000000000001924. Epub 2022 Mar 25.ABSTRACTBACKGROUND: The optimal management of asymptomatic, presumed WHO grade I meningiomas remains controversial.OBJECTIVE: To define the safety and efficacy of stereotactic…

Comparison of Active Surveillance to Stereotactic Radiosurgery for the Management of Patients with an Incidental Frontobasal Meningioma-A Sub-Analysis of the IMPASSE Study

Cancers (Basel). 2022 Mar 3;14(5):1300. doi: 10.3390/cancers14051300.ABSTRACTMeningioma is a common incidental finding, and clinical course varies based on anatomical location. The aim of this sub-analysis of the IMPASSE study was…

Stereotactic radiosurgery for intracranial chordomas: an international multiinstitutional study

J Neurosurg. 2022 Feb 4;137(4):977-984. doi: 10.3171/2021.12.JNS212416. Print 2022 Oct 1.ABSTRACTOBJECTIVE: The object of this study was to evaluate the safety, efficacy, and long-term outcomes of stereotactic radiosurgery (SRS) in…

Stereotactic radiosurgery versus active surveillance for incidental, convexity meningiomas: a matched cohort analysis from the IMPASSE study

J Neurooncol. 2022 Mar;157(1):121-128. doi: 10.1007/s11060-022-03953-5. Epub 2022 Jan 29.ABSTRACTBACKGROUND: The optimal treatment strategy of asymptomatic, convexity meningiomas, remains unclear.OBJECTIVE: The purpose of this study was to define the safety…

Stereotactic radiosurgery versus active surveillance for asymptomatic, skull-based meningiomas: an international, multicenter matched cohort study

J Neurooncol. 2022 Feb;156(3):509-518. doi: 10.1007/s11060-021-03923-3. Epub 2022 Jan 24.ABSTRACTOBJECTIVE: The optimal management of asymptomatic, skull-based meningiomas is not well defined. The aim of this study is to compare the…

Stereotactic Radiosurgery for Incidentally Discovered Cavernous Sinus Meningiomas: A Multi-institutional Study

World Neurosurg. 2022 Feb;158:e675-e680. doi: 10.1016/j.wneu.2021.11.037. Epub 2021 Nov 14.ABSTRACTBACKGROUND: The initial management of asymptomatic, incidentally discovered, cavernous sinus (CS) meningiomas remains incompletely defined. This study evaluated the safety and…

Stereotactic radiosurgery for asymptomatic petroclival region meningiomas: a focused analysis from the IMPASSE study

Acta Neurochir (Wien). 2022 Jan;164(1):273-279. doi: 10.1007/s00701-021-05056-y. Epub 2021 Nov 12.ABSTRACTBACKGROUND: The optimal management of asymptomatic, petroclival meningiomas remains incompletely defined. The purpose of this study was to evaluate the…

Radiologic and Clinical Outcomes of Stereotactic Radiosurgery for Intraventricular Metastases

World Neurosurg. 2022 Jan;157:e333-e341. doi: 10.1016/j.wneu.2021.10.083. Epub 2021 Oct 12.ABSTRACTOBJECTIVE: The optimal management of intraventricular metastases remains debatable. The aim of this study is to define the safety and efficacy…

Stereotactic radiosurgery for craniopharyngiomas

Acta Neurochir (Wien). 2021 Nov;163(11):3201-3207. doi: 10.1007/s00701-021-04990-1. Epub 2021 Sep 13.ABSTRACTBACKGROUND: The management of craniopharyngiomas is challenging, usually requiring multidisciplinary care. We evaluated the long-term clinical and radiologic outcomes of…

Diffusion weighted image documented cerebral ischemia in the postprocedural period following pipeline embolization device with shield technology treatment of unruptured intracranial aneurysms: a prospective, single center study

J Neurointerv Surg. 2020 Apr;12(4):407-411. doi: 10.1136/neurintsurg-2019-015363. Epub 2019 Sep 26.ABSTRACTOBJECTIVE: Acute ischemic stroke and silent cerebral infarctions following pipeline embolization device (PED) treatment of intracranial aneurysms have been estimated…