Clinical Trials By Division
The Adult Reconstruction division specializes in primary and revision arthroplasty of the hip and knee. Their clinical research is focused on improving outcomes in total hip and knee replacement, improving treatments of infected hip and knee replacements, and understanding the factors that contribute to complications in hip and knee replacement. We actively participate in select national and international clinical trials that can help improve the quality of care we can provide to patients.
- SWIFT – Weight loss and Knee replacement
- SWIFT study: https://clinicaltrials.gov/ct2/show/NCT02598531?term=SWIFT&rank=4
- ClinicalTrials.gov Identifier:NCT02598531
- PEPPER – Anticoagulation and Hip and Knee replacement
- https://clinicaltrials.gov/ct2/show/NCT02810704?term=PEPPER&rank=7
- ClinicalTrials.gov Identifier: NCT02810704
- Exactech – eGPS® in Total Knee Arthroplasty
- https://clinicaltrials.gov/ct2/show/NCT02962362?term=NCT02962362&rank=1
- identifier: NCT02962362
Questions? contact Eric McVey, MEd
The Orthopaedic Trauma and Oncology Division at UVA focuses on evaluation and treatment of injuries of the pelvis, leg, ankle, foot, and shoulder region. They also specialize in treatment of all types of
musculoskeletal oncology. Their clinical research focuses on ways to prevent infection in complex fractures, improving patient outcomes by evaluating different rehabilitation strategies, testing new devices designed to improve patient care, and better understanding the trauma patient population to provide the best care possible. They actively participate with the METRC group to perform these studies. METRC is composed of over 80 civilian and military trauma centers that are actively seeking to
advance care standards for patients with severe injuries. Additionally, our oncologists work with other centers to answer questions related to treatments and outcomes in patients diagnosed with cancer.
Participating center for METRC
Questions? contact: Tina Daoud
The University of Virginia Sports Medicine team takes care of athletes and non-athletes of all ages and activity levels. Our fellowship trained surgeons treat all types of injuries and conditions of the shoulder, hip and knee. The clinical trials in which we participate include evaluating new devices for multiple knee pathologies, evaluating outcomes of various hip, knee, and shoulder surgeries. In addition to our clinical trials, we participate in surgeon initiated projects of interest, cadaver based studies for surgical techniques, and studies to address clinical questions using our large databases for ACL reconstruction and patella instability.
- Articular Cartilage Defect – NOVOCART 3D Study
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- https://clinicaltrials.gov/ct2/show/NCT01957722?term=novocart&rank=3
- ClinicalTrials.gov Identifier: NCT01957722
- https://www.aesculapbiologics.com/en/patients.html
- Rotator Cuff Repair – BioWick Study
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- https://clinicaltrials.gov/ct2/show/NCT03199391?term=biowick&rank=1
- ClinicalTrials.gov Identifier: NCT03199391
- Reverse Total Shoulder Replacement- Augmented Baseplate Study
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- https://clinicaltrials.gov/ct2/show/NCT03726554?term=augmented+baseplate&rank=1
- ClinicalTrials.gov Identifier: NCT03726554
- Knee Bone Marrow Lesions– PRESERVE Study
- Knee Osteoarthritis- Calypso Knee System
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- https://clinicaltrials.gov/ct2/show/NCT03671213?term=calypso+knee+system&rank=2
- ClinicalTrials.gov Identifier: NCT03671213
- Frozen Shoulder- ZILRETTA Study
- Multi-Ligament Knee Injury- STaR Trial
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- https://clinicaltrials.gov/ct2/show/NCT03543098?term=STaR&cond=knee&rank=1
- ClinicalTrials.gov Identifier: NCT03543098
Links to UVA Clinical Trials Website For Enrolling Studies
Questions? Contact Lizzie Leitch
- Integra Cadence Total Ankle Arthroplasty Study
- https://clinicaltrials.gov/ct2/show/NCT03142958
- ClinicalTrials.gov Identifier: NCT03142958
- AMPLEX Ankle joint fusion study
- https://clinicaltrials.gov/ct2/show/NCT03028415
- ClinicalTrials.gov Identifier: NCT03028415
Questions? Contact Tina Daoud
The Spine division specializes in treating back and spine disorders. Their clinical research is broad ranging. They participate in clinical research focusing on lumbar and cervical surgical outcomes, evaluation of novel technologies to help with bone fusion, developing new diagnostics for spine problems, and developing novel treatment for common disc pathology. By performing these studies, they hope to improve the treatment quality and treatment options available to patients.
- Cervical Fusion Bone Growth Stimulator – Orthofix
- https://clinicaltrials.gov/ct2/show/NCT03177473
- ClinicalTrials.gov Identifier: NCT03177473
- Lumbar Fusion Using Trinity Elite–Orthofix
- https://clinicaltrials.gov/ct2/show/NCT02969616
- ClinicalTrials.gov Identifier: NCT02969616
- Staph Aureus Vaccine – Pfizer STRIVE study
- https://clinicaltrials.gov/ct2/show/NCT02388165
- ClinicalTrials.gov Identifier: NCT02388165
Questions? Contact Miloš Lešević
The Hand & Upper Extremity division specializes in treating acute, chronic and traumatic disorders of the elbow, hand and wrist. They are involved in clinical research pertaining to sports related injuries, peripheral nerve repair / regeneration, and outcomes related to health disparities. Additionally, the faculty and team are involved in studies looking to evaluate and improve resident and fellow education. They also routinely partner with faculty across grounds on a variety of research projects, including with the Center for Applied Biomechanics at UVA, Department of Biomedical Engineering and the Motion Analysis Lab.
- Hand Nerve Repair – Axogen
- https://clinicaltrials.gov/ct2/show/NCT01809002
- ClinicalTrials.gov Identifier: NCT01809002
Questions? Contact Miloš Lešević
The Pediatric division specializes in the musculoskeletal care of neonates, children, and adolescents. They are involved in international clinical trials as a site for the Harms Study Group evaluating the outcomes of spinal fusions and other treatments in patients with Cerebral Palsy and Scoliosis. They are also involved in clinical research focusing on the patient and surgeon expectations of different orthopaedic procedures. Through the various studies, we hope to improve the care of the patients and
the families with whom we interact.
The division is a part of the HARMS research group
- HARMS CP study
- HARMS AIS Study
Questions? Contact Nancy McKnight