Frederick H. Epstein
- BS, Physics, University of Rochester
- PhD, Biomedical Engineering, University of Virginia
Cardiovascular Magnetic Resonance Imaging; Coronary Heart Disease; Myocardial Function; Myocardial Perfusion
Imaging myocardial mechanics with Cine DENSE (Displacement Encoding with Stimulated Echoes)
MRI, including pulse sequence development and improving image analysis methods.
MRI in mouse models of cardiovascular disease.
Some projects include 3D Cine DENSE in mice, MRI of macrophage infiltration in myocardial infarction, using arterial spin labeling and first-pass MRI to quantify myocardial perfusion, T2-weighted imaging of myocardial edema, and 3D phase contrast MRI of aortic blood flow and wall shear stress, MRI of pancreatic beta cells using manganese and other targeted contrast agents as well as quantitation through MR relaxometry and multi-compartment models.