Epstein, Frederick H.

Frederick H. Epstein

Frederick H. Epstein

Primary Appointment

Professor, Biomedical Engineering

Education

  • BS, Physics, University of Rochester
  • PhD, Biomedical Engineering, University of Virginia

Contact Information


Telephone: 8049820211
Email: fhe6b@virginia.edu
Website: http://www.medicine.virginia.edu/clinical/departments/radiology/research/home.html

Research Interests

Cardiovascular Magnetic Resonance Imaging; Coronary Heart Disease; Myocardial Function; Myocardial Perfusion

Research Description

The general goal of my lab is to develop MRI techniques for assessing the structure, function, and perfusion of the cardiovascular system, particularly in the setting of coronary heart disease. Recent projects have included developing echo-planar MRI methods for imaging myocardial perfusion throughout the entire heart and developing displacement-encoded MRI for high-resolution measurements of intramyocardial motion. We have access to state-of-the-art whole body 1.5T scanners for human imaging studies and to a high-field 4.7T MRI scanner for imaging small animals, particularly mice. Through collaborations with cardiologists and molecular biologists, our novel MRI methods are applied to studies involving both clinical cardiology and basic cardiovascular science.Current Projects:

Imaging myocardial mechanics with Cine DENSE (Displacement Encoding with Stimulated Echoes) MRI, including pulse sequence development and improving image analysis methods.



MRI in mouse models of cardiovascular disease.

Selected Publications