Crawford, Matthew A.
Primary Appointment
Assistant Research Professor, Medicine: Infectious Diseases and International Health
Education
- BS, Biotechnology, Montana State University
- PhD, Microbiology, University of Virginia
- Research Fellowship, , University of Colorado
Contact Information
PO Box 801340
345 Crispell Drive, MR-6, Rm 1704
Charlotesville, Virginia 22908
Telephone: 434-924-5267
Fax: 434-924-0075
Email: mac5ee@virginia.edu
Research Disciplines
Infectious Diseases/Biodefense
Research Interests
Mechanisms of antimicrobial action and microbial strategies of resistance.
Research Description
My current research includes investigations into the emergence and dissemination of antibiotic resistance among bacterial pathogens. Especially interesting are novel examinations regarding how modifications of lipid A that confer colistin resistance impact the function and spread of other clinically relevant resistance determinants such as carbapenemases. My research also includes the development of antimicrobial, chemokine-derived peptides for use as immunostimulatory-antibiotic peptides to treat infections caused by multidrug-resistant bacterial pathogens. Additionally, as part of a collaborative effort, I am also working to develop genotypic / phenotypic diagnostic platforms to identify antibiotic resistance and inform empirical treatment.