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Archives: PhD Defenses

Yi He, PhD, 2023

5/2/2024

Islet-On-Chip and 3D Bioscaffolds for Islet Transplantation Abstract: Rationale: Pancreatic islet transplantation is a promising cell-based therapy for replacing damaged β-cells and helping restore insulin independence in Type 1 diabetes…

Karolina Dziewulska-Cronk, PhD, 2023

5/2/2024

Mechanisms of G6PD-deficient RBC Hemolysis Mediated by Oxidizing Drugs Abstract: According to estimates by the World Health Organization, around 250 million people contract Plasmodium spp. worldwide every year. While drugs…

Marissa Gonzales Stevens, PhD, 2023

5/2/2024

Modulation of Mitochondrial Dynamics and T Cell Metabolism Abstract: Following an encounter with a pathogen or vaccination, a population of memory CD8+ T cells specific for the encountered antigen remain…

Anupam Prakash, PhD, 2023

5/2/2024

Cellular and Molecular Regulators of RBC Alloimmunization Abstract: The vast majority of RBC transfusion recipients do not generate antibodies against alloantigens expressed on the RBC surface. We therefore set out…

Wei Feng Ma, PhD, 2023

5/2/2024

Investigating Atherosclerosis and Chemotherapy-Induced Cardiomyopathy at the Single Cell Resolution Abstract: Cardiovascular diseases (CVDs) and cancer are the leading causes of death worldwide. Central to many cardiovascular diseases, including myocardial…

Zollie White, PhD, 2022

9/29/2022

The Role of LKB1 in Erythropoiesis Advisor: Goldfarb, Adam, Department of Pathology, University of Virginia Abstract: Erythropoiesis is a tightly regulated multistage process in which hematopoietic stem cells (HSCs) proliferate…

Md Jashim Uddin, PhD, 2021

9/29/2022

Type 2 immunity and amebiasis Advisor: Petri, William, Medicine, Microbiology, Immunology and Cancer Biology, and Pathology, University of Virginia Abstract: The protozoan parasite Entamoeba histolytica is the causative agent of…

Aaron Stevens, PhD, 2021

9/29/2022

Intratumoral T Cell Responses to Therapeutic Vaccination and Intracranial Melanoma Advisor: Bullock, Timothy, MD-PATH Research, University of Virginia Abstract: CD8 T cells are crucial in the fight against cancer. Despite…

Morgan Simpson, PhD, 2021

9/29/2022

The Binary Toxin CDT and Toll-like Receptor 2 Contribute to the Pathogenesis of Clostridioides difficile Infection Advisor: Petri Jr., William, Infectious Disease, University of Virginia Abstract: Clostridioides difficile, the causative…

Jeremy Shaw, PhD, 2020

9/29/2022

Evaluating the Ceramide Nanoliposome as a Therapy for Head and Neck Squamous Cell Carcinoma - Circumventing Resistance, Characterizing Death, Utilizing Dual Therapies, and Manipulating Metabolism Advisor: Kester, Mark, MD-PHAR Pharmacology,…