Donna T. Chen, M.D., M.P.H (University of Virginia)
Department of Public Health Sciences,
Department of Psychiatric Medicine, and
Center for Biomedical Ethics
After completing her undergraduate education at the University of California, Berkeley where she developed her own major studying “Ethical, Political, and Social Aspect of Health and Medicine,” Donna Chen went on to the School of Medicine at the University of California, San Francisco and the School of Public Health at the University of California, Berkeley for her medical education and public health education respectively. Dr. Chen received her residency training in Psychiatry at Columbia University / New York State Psychiatric Institute, where she served as Chief Resident. She spent two years with the Southeastern Rural Mental Health Research Center at the University of Virginia , a research center funded by the National Institute of Mental Health to study the mental health service needs of underserved communities, primarily African American, impoverished, and rural communities. She was also a research fellow with the Institute of Law , Psychiatry and Public Policy and a research associate with the Center for Biomedical Ethics. During this time, she served as Associate Scientific Editor and Scientific Consultant for the Surgeon General’s report, Mental Health: Culture, Race, and Ethnicity. Dr. Chen then went to the National Institutes of Health where she received subspecialty training in Consultation-Liaison Psychiatry and completed a postdoctoral fellowship in Research Ethics.
Dr. Chen returned to the University of Virginia in 2003 as an Assistant Professor with the Department of Health Evaluation Sciences and the Department of Psychiatric Medicine and joined the Center for Biomedical Ethics in 2005. She remains a Special Volunteer with the National Institute of Mental Health. She has served on several national committees related to clinical and research ethics, including for the National Institute of Mental Health, National Institute of Neurological Diseases and Stroke, National Children’s Study, Academy of Psychosomatic Medicine , and the American Psychiatric Association.
Selected Publications and Presentations:
Chen DT, Blank MB, Worrall BB. Defending telepsychiatry: Abandon tele-health? Throwing the baby out with the bathwater (letter to the editor). Psychiatric Services, 1999; 50(2):266
Dembling BP, Chen DT, Vachon L. Life expectancy and causes of death in a population treated for serious mental illness. Psychiatric Services, 1999; 50(8):1036-1042
Chen DT, Worrall BB, Meschia JF. Protecting the privacy of family members in research (letter to the editor). JAMA, 2001; 285(15):1961-1963
Worrall BB, Chen DT (co-first author), Meschia JF. Pedigree research: ethical and methodological challenges. Stroke. 2001; 32(6):1242-1249. (Worrall and Chen contributed equally)
Chen DT, Miller FG, Rosenstein DL. Enrolling decisionally-impaired adults in clinical research. Medical Care, 2002; 40 (9, Suppl):V20-V29.
Chen DT, Miller FG, Rosenstein DL. Ethical aspects of research into the etiology of autism. Mental Retardation and Developmental Disabilities Research Reviews, 2003;9(1):48-53..
Chen DT, Miller FG, Rosenstein DL. Clinical research and the physician-patient relationship. Annals of Internal Medicine, 2003;138(8):669-72.
Chen DT. Curricular approaches to research ethics training for psychiatric investigators. Psychopharmacology (Berl). 2003 Dec;171(1):112-9. Epub 2003 May 27.
Chen DT, Worrall BB, Brott TG, Brown RD, Case D, Frankel MR, Case D, Merino JG, Silliman SL, Meschia JF. Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent: The ISGS Study. (published abstract) Stroke, 2004;35(1):311.
Chen DT, Rosenstein DL, Muthappan P, Hilsenbeck SG, Miller FG, Emanuel EJ, Wendler D. Research with stored biological samples: What do research participants want? Archives of Internal Medicine. 2005 Mar 28;165(6):652-5.
Chen DT, Worrall BB, Brown RD, Brott TG, Kissela BM, Olson TS, Rich SS, Meschia JF, for the SWISS Study Investigators. The impact of privacy protections on recruitment in a multicenter stroke genetics study. Neurology 2005 Feb 22;64(4):721-4. (Chen and Worrall contributed equally)
Worrall BB, Chen DT (co-first author), Brown RD, Jr., Brott TG, Meschia JF, for the SWISS investigators. A survey of the SWISS researchers on the impact of sibling privacy protections on pedigree recruitment. Neuroepidemiology 2005 Apr 25;25(1):32-41 (Worrall and Chen contributed equally)
Chen DT, Jones L, Gelberg L. Ethics of clinical research within a community-academic partnered participatory framework. Ethnicity and Disease (forthcoming)
REPORTS, BOOK CHAPTERS, AND BOOK REVIEWS
Lurie P, Chen D. A review of programs in North America, chapter in Dimensions of HIV Prevention: Needle Exchange. Edited by Stryker J, Smith MD. Menlo Park: Henry J. Kaiser Family Foundation. 1993
Chen D, Lurie P, Foley J. Do NEPs result in changes in community levels of drug use?, chapter in The Public Health Impact of Needle Exchange Programs in the United States and Abroad. Edited by Lurie P, Reingold A, et al. Report prepared for the Centers for Disease Control and Prevention. 1993
Chen D, Lurie P. How do NEPs operate?, chapter in The Public Health Impact of Needle Exchange Programs in the United States and Abroad. Edited by Lurie P, Reingold A, et al. Report prepared for the Centers for Disease Control and Prevention. 1993
Cournos F, Chen D. Research Strategic Planning Task Force Report. Report prepared for the New York State Office of Mental Health. 1996
Lane S, Lurie P, Bowser B, Kahn J, Chen D. The coming of age of needle exchange: A history through 1993, chapter in Harm Reduction: National and International Perspectives. Edited by Inciardi JA, Harrison LD. Thousand Oaks: Sage Press. 2000
Chen DT. Book review of In Two Minds: A Casebook of Psychiatric Ethics, by Dickenson D, Fulford KWM for Psychiatric Services, 2002; 53(8):1036-1037.
Chen DT. Clinical research. Invited entry for the Encyclopedia of Women’s Health. Edited by Loue S, Sajatovic M. Kluwer Academic/Plenum Publishing Company. 2004.
RECENT SCHOLARLY AND RESEARCH PRESENTATIONS
Chen DT. Assessing decision-making capacity. Panel at American Society for Bioethics and Humanities. Nashville, TN. October 25, 2001. (oral presentation and panel chairperson)
Other presenters: Miller FG, Rosenstein DL. Discussant: Fletcher JC.
Chen DT. Ethical implications of the psychiatric evaluation of potential donors. Symposium entitled: Evaluating potential living organ donors: Psychiatric and ethical aspects. Academy of Psychosomatic Medicine. San Antonio, TX. November 16, 2001 (oral presentation and symposium co-chairperson)
Other presenters: Crone C, Epstein S, Prager L. Discussant: Stern TA.
Chen DT. Therapeutic misconception and therapeutic intent: Where do the problems lie? Symposium entitled: The Therapeutic Misconception in Research: Barrier or Necessity? American Psychiatric Association Annual Meeting. Philadelphia, PA. May 21, 2002. (oral presentation)
Other presenters: Candilis PJ, Lidz CW, Kim SY, Belkin G
Chen DT, Rosenstein DL. What is different about psychiatric consultations in clinical research? Academy of Psychosomatic Medicine Annual Meeting. Tucson, AZ. November 23, 2002 (oral presentation)
Chen DT. Informed consent, recruitment, and research ethics. Workshop on Clinical Trials in Psychopharmacology. American Society of Clinical Psychopharmacology. New York, NY. April 30, 2003. (oral presentation).
Chen DT, Rosenstein DL, Miller FG, Hilsenbeck SG, Muthappan G, Emanuel EJ, Wendler D. Most research subjects permit use of biological samples in future research. American Society of Clinical Oncology. Chicago, IL. June 1, 2003. (poster discussion presentation)
Chen DT. Collaborating with communities to enhance ethics of research. Roundtable/Scientific Discussion Panel entitled: Data and Safety Monitoring in Prevention Research. Society for Prevention Research. Washington, DC. June 12, 2003 (panel presentation).
Other presenters: Pearson J, Schwartz J, Sims B, Crump A, Moten C, Levin N, Volkow M.
Chen DT. Ethics and Clinical Research. South Central Mental Illness Research, Education, and Clinical Center (MIRECC) Leadership Conference. Houston, TX. June 27, 2003. (featured speaker)
Chen DT. Does Psychosomatic Medicine Need a Code of Ethics. Academy of Psychosomatic Medicine Annual Meeting, San Diego. November 22, 2003. (roundtable presentation and discussion leader).
Chen DT, Worrall BB, Brott TG, Brown RD, Case D, Frankel MR, Merino JG, Silliman SL, Meschia JF. Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent: The ISGS Study. American Stroke Association Annual Meeting, San Diego, CA. February 2004 (poster presentation)
Chen DT. Informed consent, recruitment, and research ethics. Workshop on Clinical Trials in Psychopharmacology. American Society of Clinical Psychopharmacology. New York, NY. April 21, 2004. (oral presentation)
Worrall BB, Chen DT, Olson T, Meschia JF. Recruitment of sib-pairs into SWISS: Balancing ethical and scientific considerations. American Academy of Neurology 56th Annual Meeting. San Francisco, CA. April 27, 2004 (poster presentation)
Blackman SB, Bovbjerg VE, Chen DT, Lombardo PA, Riffenburgh A, Stevenson RD. Readability of Pediatric Research Consent Forms. University of Virginia Children’s Medical Center Research Day. Charlottesville, VA. May 20, 2004 (poster presentation)
Chen DT. Ethical challenges in clinical research. 44thAnnual New Clinical Drug Evaluation Unit (NCDEU). Phoenix, AZ. June 1, 2004. (workshop panel oral presentation, Other panelists: Shore D, NIMH; Blader D, Stony Brook; Moderator: Goldstein H, APA)
Chen DT. Clinical Research Ethics. Workshop on Clinical Trials in Psychopharmacology. American Society of Clinical Psychopharmacology. New York, NY. April 12, 2005. (oral presentation)