[Jordan 1-17] Hosted by Norbert Leitinger.
Laszlo Nagy’s Research Focus
Dr. Nagy is a physician by training and a molecular and cell biologist with a long-standing research interest in the biology of gene-expression regulation, cellular differentiation, and their contribution to human diseases. The fundamental question he raises in his research is how lipid signaling regulates gene expression and how a changing extra- and intracellular lipid environment impacts the expression of the genome and contributes to changing cellular phenotypes. He uses the paradigm of nuclear hormone receptor activation/signaling and the contribution of this process to myeloid cell differentiation, function, and to diseases, involving these cells, such as atherosclerosis, tissue regeneration, metabolic, and various inflammatory disorders, as his model systems. He uses genome-wide and epigenomic approaches along with bioinformatics and data integration.