James Radford Stone
Professor of Radiology and Medical Imaging, Radiology and Medical Imaging
Bio & Overview
Academic Information
- Department
- Radiology and Medical Imaging
- Academic Title
- Associate Professor
Primary Education
- BS, Biology, Virginia Commonwealth University, 1995
- PhD, Anatomy and Neurobiology, Medical College of Virginia, Virginia Commonwealth University, 2000
- MD, Medicine, University of Virginia, 2004
Other Appointments
- Neuroscience
- Associate Professor, Neurosurgery
Other Affiliations
- Member, Cancer Center
- Associate Professor, BIMS
Research Interests
Research Disciplines
- Neuroscience
Research Opportunities
- Neuroscience
PhD Programs
- Neuroscience
Selected Publications
2024
Stone, J. R., Avants, B. B., Tustison, N. J., Gill, J., Wilde, E. A., Neumann, K. D., . . . Ahlers, S. T. (2024). Neurological Effects of Repeated Blast Exposure in Special Operations Personnel. JOURNAL OF NEUROTRAUMA, 41(7-8), 942-956. doi:10.1089/neu.2023.0309
2022
Vorn, R., Edwards, K. A., Hentig, J., Yun, S., Kim, H. -S., Lai, C., . . . Gill, J. M. (2022). A Pilot Study of Whole-Blood Transcriptomic Analysis to Identify Genes Associated with Repetitive Low-Level Blast Exposure in Career Breachers. BIOMEDICINES, 10(3). doi:10.3390/biomedicines10030690
Wilde, E. A., Wanner, I. -B., Kenney, K., Gill, J., Stone, J. R., Disner, S., . . . Jeromin, A. (2022). A Framework to Advance Biomarker Development in the Diagnosis, Outcome Prediction, and Treatment of Traumatic Brain Injury. JOURNAL OF NEUROTRAUMA, 39(7-8), 436-457. doi:10.1089/neu.2021.0099
Edwards, K. A., Leete, J. J., Smith, E. G., Quick, A., Modica, C. M., Wassermann, E. M., . . . Gill, J. M. (2022). Elevations in Tumor Necrosis Factor Alpha and Interleukin 6 From Neuronal-Derived Extracellular Vesicles in Repeated Low-Level Blast Exposed Personnel. FRONTIERS IN NEUROLOGY, 13. doi:10.3389/fneur.2022.723923
Qing, K., Nie, K., Liu, B., Feng, X., Stone, J. R., Cui, T., . . . Chundury, A. (2022). The Impact of Optic Nerve Movement on Intracranial Radiation Treatment. FRONTIERS IN ONCOLOGY, 12. doi:10.3389/fonc.2022.803329
2021
Edwards, K. A., Greer, K., Leete, J., Lai, C., Devoto, C., Qu, B. -X., . . . Gill, J. M. (2021). Neuronally-derived tau is increased in experienced breachers and is associated with neurobehavioral symptoms. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-97913-0
Haran, F. J., Zampieri, C., Wassermann, E. M., Polejaeva, E., Dell, K. C., LoPresti, M. L., . . . Carr, W. (2021). Chronic Effects of Breaching Blast Exposure on Sensory Organization and Postural Limits of Stability. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 63(11), 944-950. doi:10.1097/JOM.0000000000002266
Tustison, N. J., Cook, P. A., Holbrook, A. J., Johnson, H. J., Muschelli, J., Devenyi, G. A., . . . Avants, B. B. (2021). The ANTsX ecosystem for quantitative biological and medical imaging. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-87564-6
Avants, B. B., Tustison, N. J., & Stone, J. R. (2021). Similarity-driven multi-view embeddings from high-dimensional biomedical data. NATURE COMPUTATIONAL SCIENCE, 1(2), 143-152. doi:10.1038/s43588-021-00029-8
Bailes, J. E., Bramlett, H. M., Brody, D. L., Buki, A., Bullock, R., Dietrich, W. D., . . . Vink, R. B. (2021). Tribute to John T. Povlishock, PhD TRIBUTE. JOURNAL OF NEUROTRAUMA, 38(14), 1890-1903. doi:10.1089/neu.2021.29113.jtp.tribute
2020
Stone, J. R., Avants, B. B., Tustison, N. J., Wassermann, E. M., Gill, J., Polejaeva, E., . . . Ahlers, S. T. (2020). Functional and Structural Neuroimaging Correlates of Repetitive Low-Level Blast Exposure in Career Breachers. JOURNAL OF NEUROTRAUMA, 37(23), 2468-2481. doi:10.1089/neu.2020.7141
Dickstein, D. L., De Gasperi, R., Gama Sosa, M. A., Perez-Garcia, G., Short, J. A., Sosa, H., . . . Elder, G. A. (2021). Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure. MOLECULAR PSYCHIATRY, 26(10), 5940-5954. doi:10.1038/s41380-020-0674-z
Modica, C. M., Johnson, B. R., Zalewski, C., King, K., Brewer, C., King, J. E., . . . Carr, W. (2020). Hearing Loss and Irritability Reporting Without Vestibular Differences in Explosive Breaching Professionals. FRONTIERS IN NEUROLOGY, 11. doi:10.3389/fneur.2020.588377
2019
Abutarboush, R., Gu, M., Kawoos, U., Mullah, S. H., Chen, Y., Goodrich, S. Y., . . . Ahlers, S. T. (2019). Exposure to Blast Overpressure Impairs Cerebral Microvascular Responses and Alters Vascular and Astrocytic Structure. JOURNAL OF NEUROTRAUMA, 36(22), 3138-3157. doi:10.1089/neu.2019.6423
Bigler, E. D., Abildskov, T. J., Eggleston, B., Taylor, B. A., Tate, D. F., Petrie, J. A., . . . Wilde, E. A. (2019). Structural neuroimaging in mild traumatic brain injury: A chronic effects of neurotrauma consortium study. INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, 28(3). doi:10.1002/mpr.1781
Cao, R., Zhang, C., Mitkin, V. V., Lankford, M. F., Li, J., Zuo, Z., . . . Hu, S. (2019). Comprehensive Characterization of Cerebrovascular Dysfunction in Blast Traumatic Brain Injury Using Photoacoustic Microscopy. JOURNAL OF NEUROTRAUMA, 36(10), 1526-1534. doi:10.1089/neu.2018.6062
Hsu, A., Bhattacharya, K. R., Chan, H. K., Huber, T. C., Gardner, B., Stone, J. R., & Angle, J. F. (2019). Effect of timing on endovascular therapy and exploratory laparotomy outcome in acute mesenteric ischemia. ANNALS OF GASTROENTEROLOGY, 32(6), 600-604. doi:10.20524/aog.2019.0419
Tustison, N. J., Holbrook, A. J., Avants, B. B., Roberts, J. M., Cook, P. A., Reagh, Z. M., . . . Yassa, M. A. (2019). Longitudinal Mapping of Cortical Thickness Measurements: An Alzheimer's Disease Neuroimaging Initiative-Based Evaluation Study. JOURNAL OF ALZHEIMERS DISEASE, 71(1), 165-183. doi:10.3233/JAD-190283
2018
Bigler, E. D., Skiles, M., Wade, B. S. C., Abildskov, T. J., Tustison, N. J., Scheibel, R. S., . . . Wilde, E. A. (2020). FreeSurfer 5.3 versus 6.0: are volumes comparable? A Chronic Effects of Neurotrauma Consortium study. BRAIN IMAGING AND BEHAVIOR, 14(5), 1318-1327. doi:10.1007/s11682-018-9994-x
2017
Wilkins, L. R., Stone, J. R., Mata, J., Hawrylack, A., Kubicka, E., & Brautigan, D. L. (2017). The Use of the Woodchuck as an Animal Model for Evaluation of Transarterial Embolization. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 28(10), 1467-1471. doi:10.1016/j.jvir.2017.04.005
Hohenwalter, E. J., Stone, J. R., O'Moore, P. V., Smith, S. J., Selby, J. B., Lewandowski, R. J., . . . Rilling, W. S. (2017). Multicenter Trial of the VenaTech Convertible Vena Cava Filter. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 28(10), 1353-1362. doi:10.1016/j.jvir.2017.06.032
Huber, T., Wilkins, L. R., Sabri, S., Park, A. W., Stone, J. R., Angle, J. F., . . . Matsumoto, A. H. (2017). Midterm Follow-up of Ureteral Embolization Using Vascular Plugs and N-Butyl Cyanoacrylate Glue. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 28(8), 1123-1128. doi:10.1016/j.jvir.2017.02.026
2016
Perez-Garcia, G., Sosa, M. A. G., De Gasperi, R., Lashof-Sullivan, M., Maudlin-Jeronimo, E., Stone, J. R., . . . Elder, G. A. (2018). Chronic post-traumatic stress disorder-related traits in a rat model of low-level blast exposure. BEHAVIOURAL BRAIN RESEARCH, 340, 117-125. doi:10.1016/j.bbr.2016.09.061
Dickstein, D. L., Pullman, M. Y., Fernandez, C., Short, J. A., Kostakoglu, L., Knesaurek, K., . . . Gandy, S. (2016). Cerebral [18F]T807/AV1451 retention pattern in clinically probable CTE resembles pathognomonic distribution of CTE tauopathy. TRANSLATIONAL PSYCHIATRY, 6. doi:10.1038/tp.2016.175
Carr, W., Stone, J. R., Walilko, T., Young, L. A., Snook, T. L., Paggi, M. E., . . . Ahlers, S. T. (2016). Repeated Low-Level Blast Exposure: A Descriptive Human Subjects Study. MILITARY MEDICINE, 181(5), 28-39. doi:10.7205/MILMED-D-15-00137
Wilde, E. A., Bigler, E. D., Huff, T., Wang, H., Black, G. M., Christensen, Z. P., . . . Tate, D. F. (2016). Quantitative structural neuroimaging of mild traumatic brain injury in the Chronic Effects of Neurotrauma Consortium (CENC): Comparison of volumetric data within and across scanners. BRAIN INJURY, 30(12), 1442-1451. doi:10.1080/02699052.2016.1219063
Stone, J. R., Wilde, E. A., Taylor, B. A., Tate, D. F., Levin, H., Bigler, E. D., . . . Tustison, N. J. (2016). Supervised learning technique for the automated identification of white matter hyperintensities in traumatic brain injury. BRAIN INJURY, 30(12), 1458-1468. doi:10.1080/02699052.2016.1222080
Perez-Garcia, G., Sosa, M. A. G., De Gasperi, R., Lashof-Sullivan, M., Maudlin-Jeronimo, E., Stone, J. R., . . . Elder, G. A. (2016). Exposure to a Predator Scent Induces Chronic Behavioral Changes in Rats Previously Exposed to Low-level Blast: Implications for the Relationship of Blast-Related TBI to PTSD. FRONTIERS IN NEUROLOGY, 7. doi:10.3389/fneur.2016.00176
2015
Wilde, E. A., Bouix, S., Tate, D. F., Lin, A. P., Newsome, M. R., Taylor, B. A., . . . York, G. (2015). Advanced neuroimaging applied to veterans and service personnel with traumatic brain injury: state of the art and potential benefits. BRAIN IMAGING AND BEHAVIOR, 9(3), 367-402. doi:10.1007/s11682-015-9444-y
Contrella, B. N., Sabri, S. S., Tracci, M. C., Stone, J. R., Kern, J. A., Upchurch, G. R., . . . Angle, J. F. (2015). Outcomes of Coverage of the Left Subclavian Artery during Endovascular Repair of the Thoracic Aorta. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 26(11), 1609-1614. doi:10.1016/j.jvir.2015.07.022
Stone, J. R., & Wilkins, L. R. (2015). Acute mesenteric ischemia.. Techniques in vascular and interventional radiology, 18(1), 24-30. doi:10.1053/j.tvir.2014.12.004
Wintermark, M., Coombs, L., Druzgal, T. J., Field, A. S., Filippi, C. G., Hicks, R., . . . Provenzale, J. M. (2015). Traumatic Brain Injury Imaging Research Roadmap. AMERICAN JOURNAL OF NEURORADIOLOGY, 36(3), E12-E23. doi:10.3174/ajnr.A4254
Stone, J. R., & Sabri, S. S. (2015). Introduction. TECHNIQUES IN VASCULAR AND INTERVENTIONAL RADIOLOGY, 18(1), 1. doi:10.1053/j.tvir.2014.12.001
Stone, J. R., & Wilkins, L. R. (2015). Acute Mesenteric Ischemia. TECHNIQUES IN VASCULAR AND INTERVENTIONAL RADIOLOGY, 18(1), 24-30. doi:10.1053/j.tvir.2014.12.004
Elder, G. A., Sosa, M. A. G., De Gasperi, R., Stone, J. R., Dickstein, D. L., Haghighi, F., . . . Ahlers, S. T. (2015). Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury. FRONTIERS IN NEUROLOGY, 6. doi:10.3389/fneur.2015.00048
2014
Wilkins, L. R., & Stone, J. R. (2015). Chronic Mesenteric Ischemia. TECHNIQUES IN VASCULAR AND INTERVENTIONAL RADIOLOGY, 18(1), 31-37. doi:10.1053/j.tvir.2014.12.005
Sabri, S. S., Hendricks, N., Stone, J., Tracci, M. C., Matsumoto, A. H., & Angle, J. F. (2015). Retrograde Pedal Access Technique for Revascularization of Infrainguinal Arterial Occlusive Disease. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 26(1), 29-38. doi:10.1016/j.jvir.2014.10.008
Gandy, S., Ikonomovic, M. D., Mitsis, E., Elder, G., Ahlers, S. T., Barth, J., . . . DeKosky, S. T. (2014). Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. MOLECULAR NEURODEGENERATION, 9. doi:10.1186/1750-1326-9-37
Hendricks, N. J., Matsumoto, A. H., Angle, J. F., Baheti, A., Sabri, S. S., Park, A. W., . . . Cutlip, D. E. (2014). Is fibromuscular dysplasia underdiagnosed? A comparison of the prevalence of FMD seen in CORAL trial participants versus a single institution population of renal donor candidates. VASCULAR MEDICINE, 19(5), 363-367. doi:10.1177/1358863X14544715
Tustison, N. J., Cook, P. A., Klein, A., Song, G., Das, S. R., Duda, J. T., . . . Avants, B. B. (2014). Large-scale evaluation of ANTs and FreeSurfer cortical thickness measurements. NEUROIMAGE, 99, 166-179. doi:10.1016/j.neuroimage.2014.05.044
Elder, G. A., Stone, J. R., & Ahlers, S. T. (2014). Effects of low-level east exposure on the nervous system: is there really a controversy?. FRONTIERS IN NEUROLOGY, 5. doi:10.3389/fneur.2014.00269
Banizs, A. B., Huang, T., Dryden, K., Berr, S. S., Stone, J. R., Nakamoto, R. K., . . . He, J. (2014). In vitro evaluation of endothelial exosomes as carriers for small interfering ribonucleic acid delivery. INTERNATIONAL JOURNAL OF NANOMEDICINE, 9, 4223-4230. doi:10.2147/IJN.S64267
2013
Rueb, G. R., Brady, W. J., Gilliland, C. A., Patrie, J. T., Saad, W. E., Sabri, S. S., . . . Angle, J. F. (2013). Characterizing Cardiopulmonary Arrest during Interventional Radiology Procedures. JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 24(12), 1774-1778. doi:10.1016/j.jvir.2013.07.017
Choudhri, A. F., Norton, P. T., Carr, T. M. I. I. I., Stone, J. R., Hagspiel, K. D., & Dake, M. D. (2013). Diagnosis and treatment planning of acute aortic emergencies using a handheld DICOM viewer. EMERGENCY RADIOLOGY, 20(4), 267-272. doi:10.1007/s10140-013-1118-8
2012
Tustison, N. J., Avants, B. B., Cook, P. A., Kim, J., Whyte, J., Gee, J. C., & Stone, J. R. (2014). Logical circularity in voxel-based analysis: Normalization strategy may induce statistical bias. HUMAN BRAIN MAPPING, 35(3), 745-759. doi:10.1002/hbm.22211
Saad, W. E. A., Kalagher, S., Turba, U. C., Sabri, S. S., Park, A. -W., Stone, J., . . . Matsumoto, A. H. (2013). Ureteric Embolization for Lower Urinary Tract Fistulae: Use of Two Amplatzer Vascular Plugs and N-Butyl Cyanoacrylate Employing the "Sandwich" Technique. CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 36(4), 1068-1072. doi:10.1007/s00270-012-0510-1
Ahlers, S. T., Vasserman-Stokes, E., Shaughness, M. C., Hall, A. A., Shear, D. A., Chavko, M., . . . Stone, J. R. (2012). Assessment of the effects of acute and repeated exposure to blast overpressure in rodents: toward a greater understanding of blast and the potential ramifications for injury in humans exposed to blast.. Frontiers in neurology, 3, 32. doi:10.3389/fneur.2012.00032
2011
Choudhri, A. F., Carr, T. M. I. I. I., Ho, C. P., Stone, J. R., Gay, S. B., & Lambert, D. L. (2012). Handheld Device Review of Abdominal CT for the Evaluation of Acute Appendicitis. JOURNAL OF DIGITAL IMAGING, 25(4), 492-496. doi:10.1007/s10278-011-9431-9