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Research Groups and Labs

UVA Infectious Disease LabResearch is supported by more than $29 million in annual extramural funding in eight departments and four divisions in the School of Medicine, including global health initiatives supported by the Bill & Melinda Gates Foundation and the NIH, and carried out with partners in countries around the world, among them Bangladesh, Brazil, Haiti, South Africa, Tanzania, and Uganda.

 

 

Chelsea Marie Braun, PhD

Chelsea Marie Braun PhDPRIMARY APPOINTMENT:

Medicine, Infectious Disease and International Health

RESEARCH AREAS:

The Marie lab is focused on understanding host-pathogen interactions of intestinal pathogens. We focus on Cryptosporidium, a critically important pediatric diarrheal pathogen. In 2016, Cryptosporidium was the fifth leading diarrheal pathogen in children under five years, causing ~48,000 deaths and the loss of > 4.2 million disability-adjusted life-years (DALYs). Cryptosporidium is associated with growth faltering in children, making this a key pathogen for intervention.

Scott Heysell, MD, MPH

Photo of SCOTT HEYSELLPRIMARY APPOINTMENT:

Thomas H. Hunter Professor of International Medicine

RESEARCH:

The research group focuses on optimizing technologies and gaining a better understanding of anti-tuberculosis (TB) drug pharmacokinetics and pharmacodynamics to improve treatment outcomes in patients with mycobacterial diseases or with comorbid HIV, diabetes, and/or malnutrition. Consequent secondary areas of interest include the development of laboratory assays for pharmacokinetic and pharmacodynamic studies, the building of infrastructure for community-based research in TB-endemic settings, clinical trials of TB drug regimens, machine learning analyses for outcomes prediction, and health systems research for growing equity-based solutions to social drivers of health.

Eric Houpt, MD

Eric Houpt, MD

PRIMARY APPOINTMENT:

Professor, Division Head, Infectious Disease and International Health

RESEARCH AREAS:

The Houpt Group Laboratory, within the Division of Infectious Diseases and International Health, is involved in projects focused on molecular diagnostic tools for infectious diseases. We seek a research diagnostic that can rapidly and accurately identify agents of acute febrile illnesses and develop panels of PCR-based diagnostic tests to detect a full range of enteropathogens.

We focus on tuberculosis research, aiming to improve patient outcomes by developing rapid diagnostics that can identify the most effective drugs to use and identify markers for poor therapeutic response.

 

William A. Petri, Jr, MD PhD

Dr. William Petri, MD, PhDPRIMARY APPOINTMENT:

    • Wade Hampton Frost Professor of Medicine and Vice Chair for Research, Department of Medicine
    • Professor of Medicine – Microbiology, Immunology and Cancer Biology; Pathology; Medicine- Infectious Diseases and International Health

RESEARCH AREAS:

William A. Petri, Jr, MD PhD, studies immunology and molecular pathogenesis of infectious diseases and their consequences. The scope of the research encompasses immunopathogenesis and vaccine development for COVID-19, molecular parasitology of Entamoeba, innate immune host defense against Clostridium difficile, and acquired immunity to Cryptosporidium in Bangladesh. We study infections in mouse models, in humans (including clinical trials), and in the laboratory.

Mami Taniuchi, PhD

Mami Taniuchi PhD photo credit Kim Kelley-WagnerPRIMARY APPOINTMENT:

Associate Professor of Medicine: Infectious Diseases
and International Health,

Biomedical Engineering and Engineering Systems and
Environment

RESEARCH AREAS:

Environmental Surveillance; Molecular diagnostics; Polio eradication; tracking immunity and virus shedding after oral polio vaccination in resource-challenged countries.

Tania A. Thomas, MD MPH

Photo of TANIA THOMASPRIMARY APPOINTMENT:

Associate Professor
Department of Medicine, Division of Infectious Diseases and International Health

RESEARCH AREAS:

Tuberculosis, childhood tuberculosis, biomarkers, HIV, HPV-related anal dysplasia